(Q46450503)

22 December 2017

title

Interleukin-4 signaling in B lymphocytes from patients with X-linked severe combined immunodeficiency (English)

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22 December 2017

severe combined immunodeficiency

main subject

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Taylor N

1

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22 December 2017

Candotti F

2

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22 December 2017

Smith S

3

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22 December 2017

Oakes SA

4

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22 December 2017

Jahn T

5

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22 December 2017

Isakov J

6

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22 December 2017

Puck JM

7

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22 December 2017

O'Shea JJ

8

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22 December 2017

Weinberg K

9

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22 December 2017

Johnston JA

10

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22 December 2017

language of work or name

English

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publication date

1 March 1997

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22 December 2017

Journal of Biological Chemistry

published in

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22 December 2017

volume

272

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22 December 2017

issue

11

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22 December 2017

page(s)

7314-7319

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22 December 2017

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin-2 (IL-2) receptor gamma chain mutations in X-linked severe combined immunodeficiency disease result in the loss of high-affinity IL-2 receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Cytokine receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Cytokine signaling through nonreceptor protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

An interleukin-4-induced transcription factor: IL-4 Stat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of J

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Essential role of Stat6 in IL-4 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Female germ line mosaicism as the origin of a unique IL-2 receptor gamma-chain mutation causing X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Characterization of the promoter of the human gene encoding the high-affinity IgG receptor: transcriptional induction by gamma-interferon is mediated through common DNA response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

IL-4 and IL-13 receptors: are they one and the same?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Signal transduction through the IL-4 and insulin receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Characterization and comparison of the interleukin 13 receptor with the interleukin 4 receptor on several cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140-kDa subunit of the interleukin 4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.11.7314

21 January 2018

Identifiers

DOI

10.1074/JBC.272.11.7314

1 reference

22 December 2017

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22 December 2017