(Q46459537)

English

Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis

scientific article published in January 2009

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scholarly article

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis (English)

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

amyotrophic lateral sclerosis

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1 reference

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author name string

Chrissandra J Zagami

1

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

Philip M Beart

2

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

Nicole Wallis

3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

Phillip Nagley

4

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

Ross D O'Shea

5

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

publication date

1 January 2009

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

57

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

2

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

119-135

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

21 January 2018

The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

21 January 2018

Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

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Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

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A neuron-glia signalling network in the active brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

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4-hydroxynonenal, a lipid peroxidation product, impairs glutamate transport in cortical astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

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ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

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Oxidative stress induced by glutamate receptor agonists

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

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Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

New insights into neuron-glia communication

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid trafficking of the neuronal glutamate transporter, EAAC1: evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Regional deafferentation down-regulates subtypes of glutamate transporter proteins

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the AMPA-activated receptors present on motoneurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutant CuZn superoxide dismutase in motor neuron disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of glial fibrillary acidic protein results in decreased glutamate transport and inhibition of PKA-induced EAAT2 cell surface trafficking

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

(S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of glial glutamate transporters after glutamatergic denervation in the rat brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Protective Role of Reactive Astrocytes in Brain Ischemia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of Disease: astrocytes in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate-induced up-regulation of Na(+)-dependent glutamate transport activity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Excitatory amino acids and neuropsychiatric disorders

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocyte activation and reactive gliosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Reactive astrocytes: cellular and molecular cues to biological function

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetics of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis in amyotrophic lateral sclerosis--what is the evidence?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrogliosis in ALS: possible interpretations according to pathogenetic hypotheses

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered in-vitro and in-vivo expression of glial glutamate transporter-1 following exposure to cerebrospinal fluid of amyotrophic lateral sclerosis patients.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning, transport properties, and differential localization of two splice variants of GLT-1 in the rat CNS: implications for CNS glutamate homeostasis.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxynitrite inhibits glutamate transporter subtypes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

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Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20739

7 January 2021

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Identifiers

10.1002/GLIA.20739

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18661557

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