(Q46459968)

22 December 2017

title

Dual drug interactions via P-glycoprotein (P-gp)/ cytochrome P450 (CYP3A4) interplay: recent case study of oral atorvastatin and verapamil (English)

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22 December 2017

author name string

Nuggehally R Srinivas

series ordinal

1

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22 December 2017

publication date

26 July 2008

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22 December 2017

European Journal of Clinical Pharmacology

published in

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22 December 2017

volume

64

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22 December 2017

issue

11

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22 December 2017

page(s)

1135-1136

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22 December 2017

An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constituents.

cites work

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12 December 2020

The intestinal first-pass metabolism of substrates of CYP3A4 and P-glycoprotein-quantitative analysis based on information from the literature

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12 December 2020

Lessons learned from the irinotecan metabolic pathway

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12 December 2020

Transporter-Enzyme Interactions: Implications for Predicting Drug-Drug Interactions from In Vitro Data

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12 December 2020

Validation of the hepatic blood flow rate model for verapamil first-pass metabolism

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12 December 2020

Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption

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12 December 2020

Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.

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12 December 2020

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

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12 December 2020

Influence of P-glycoprotein on the transport and metabolism of indinavir in Caco-2 cells expressing cytochrome P-450 3A4

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12 December 2020

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

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12 December 2020

Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations

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12 December 2020

Effect of atorvastatin and fluvastatin on the metabolism of midazolam by cytochrome P450 in vitro

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12 December 2020

Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

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12 December 2020

Combined therapy with atorvastatin and calcineurin inhibitors: no interactions with tacrolimus

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12 December 2020

Role of P-glycoprotein in statin drug interactions

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12 December 2020

Serum Rifampicin Levels in Patients with Tuberculosis : Effect of P-Glycoprotein and CYP3A4 Blockers on its Absorption

1 reference

12 December 2020

Drug interaction between oral atorvastatin and verapamil in healthy subjects: effects of atorvastatin on the pharmacokinetics of verapamil and norverapamil

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12 December 2020

Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: consequences for FK506 assimilation

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12 December 2020

Unmasking the dynamic interplay between efflux transporters and metabolic enzymes.

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12 December 2020

The drug efflux-metabolism alliance: biochemical aspects.

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12 December 2020

Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions

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12 December 2020

10.1007/S00228-008-0512-8

Identifiers

DOI

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22 December 2017

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22 December 2017