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The drug efflux-metabolism alliance: biochemical aspects.
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
The drug efflux-metabolism alliance: biochemical aspects
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author
Carolyn L. Cummins
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author name string
L Z Benet
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
language of work or name
English
0 references
publication date
1 October 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
published in
Advanced Drug Delivery Reviews
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
volume
50 Suppl 1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
page(s)
S3-11
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
cites work
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
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Effect of food on the pharmacokinetics of cyclosporine in healthy subjects following oral and intravenous administration
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Crossref
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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
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Absorption kinetics of cyclosporine in healthy volunteers
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-fat meals increase the clearance of cyclosporine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transport and metabolism of cyclosporine in isolated rat hepatocytes. The effects of lipids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
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CYP3A gene expression in human gut epithelium
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine*
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tacrolimus oral bioavailability doubles with coadministration of ketoconazole
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers
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Crossref
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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetic interactions between HIV-protease inhibitors in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of ketoconazole on digoxin absorption and disposition in rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of saquinavir on the pharmacokinetics and pharmacodynamics of oral and intravenous midazolam.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for different ABC-transporters in Caco-2 cells modulating drug uptake
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900178-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0169-409X(01)00178-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
PubMed publication ID
11576692
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11576692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11576692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
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