(Q46467755)

English

An in vitro model for assessment of drug-induced torsade de pointes arrhythmia : effects of haloperidol and dofetilide on potential duration, repolarization inhomogeneities, and torsade de pointes arrhythmia

scientific article published on 22 July 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

An in vitro model for assessment of drug-induced torsade de pointes arrhythmia : effects of haloperidol and dofetilide on potential duration, repolarization inhomogeneities, and torsade de pointes arrhythmia (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

1 reference

based on heuristic

inferred from title

author name string

Stefan Dhein

1

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

Franziska Perlitz

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

Friedrich-Wilhelm Mohr

3

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

publication date

22 July 2008

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

378

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

6

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

631-644

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

https://scigraph.springernature.com/pub.10.1007/s00210-008-0329-0

0 references

Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0329-0

21 January 2018

Sex difference in risk of torsade de pointes with d,l-sotalol

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0329-0

21 January 2018

The association between intravenous haloperidol and Torsades de Pointes. Three cases and a literature review

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0329-0

21 January 2018

Risk factors and predictors of Torsade de pointes ventricular tachycardia in patients with left ventricular systolic dysfunction receiving Dofetilide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Torsades de pointes ventricular tachyarrhythmia associated with haloperidol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiologic substrate of torsade de pointes: dispersion of repolarization or early afterdepolarizations?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spread of activation in the left ventricular wall of the dog. II. Activation conditions at the epicardial surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The utility of hERG and repolarization assays in evaluating delayed cardiac repolarization: influence of multi-channel block

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interventricular dispersion of repolarization in acquired torsade-de-pointes arrhythmias: reversal by magnesium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tridimensional activation patterns of acquired torsade-de-pointes tachycardias in dogs with chronic AV-block

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-induced torsade de pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of QT interval in isolated feline hearts by antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method for analysing the geometry and timecourse of epicardial potential spreading

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of class III antiarrhythmic agents in an in vitro rabbit model of spontaneous torsades de pointe

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optical Mapping of Drug-Induced Polymorphic Arrhythmias and Torsade de Pointes in the Isolated Rabbit Heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Twisting of the points

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged Q-T interval and hypokalemia caused by haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of D-sotalol, quinidine, and amiodarone on dispersion of ventricular repolarization in the isolated rabbit heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine-induced action potential prolongation, early afterdepolarizations, and triggered activity in canine Purkinje fibers. Effects of stimulation rate, potassium, and magnesium

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prearrhythmia: changes preceding arrhythmia, new aspects by epicardial mapping

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiarrhythmic efficacy of a new class III agent, UK-68,798, during chronic myocardial infarction: evaluation using three-dimensional mapping

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Drug-induced long QT syndrome and torsade de pointes arrhythmias]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative study on the proarrhythmic effects of some antiarrhythmic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of proarrhythmia in the female rabbit heart: blinded validation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells (M cells) in the canine heart: quinidine and digitalis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic effect of continuous vs intermittent dosing of dofetilide on QT interval

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between refractory periods and activation-recovery intervals from electrograms: effects of rate and adrenergic interventions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiologic profile and efficacy of intravenous dofetilide (UK-68,798), a new class III antiarrhythmic drug, in patients with sustained monomorphic ventricular tachycardia. Dofetilide Arrhythmia Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Torsade de pointes induced by psychotropic drugs and the prevalence of its risk factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of intravenous haloperidol on QT interval dispersion in critically ill patients: comparison with QT interval prolongation for assessment of risk of Torsades de Pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of pause-induced torsade de pointes in long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rate- and site-dependent effects of propafenone, dofetilide, and the new I(Ks)-blocking agent chromanol 293b on individual muscle layers of the intact canine heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of arrhythmogenicity of the short-long cardiac sequence that precedes ventricular tachyarrhythmias in the long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dofetilide block involves interactions with open and inactivated states of HERG channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of the corrected QT and torsades de pointes cardiac arrhythmia associated with intravenous haloperidol in the medically ill.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential fields on the ventricular surface of the exposed dog heart during normal excitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High affinity open channel block by dofetilide of HERG expressed in a human cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The potential of epicardial activation mapping in isolated hearts for the assessment of arrhythmogenic and antiarrhythmic drug activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial heterogeneity of myocardial perfusion predicts local potassium channel expression and action potential duration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol-induced torsades de pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life-Threatening Ventricular Arrhythmia (Torsades de Pointes) after Haloperidol Overdose

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors affecting epicardial dispersion of repolarization: a mapping study in the isolated porcine heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical antipsychotics: from potassium channels to torsade de pointes and sudden death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Torsades de Pointes associated with intravenous haloperidol in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dofetilide: A new antiarrhythmic agent approved for conversion and/or maintenance of atrial fibrillation/atrial flutter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-008-0329-0

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18648775

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