(Q46479032)

22 December 2017

title

The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection (English)

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22 December 2017

author name string

Akashi K

series ordinal

1

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22 December 2017

Weissman IL

series ordinal

2

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22 December 2017

language of work or name

English

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publication date

1 August 1996

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22 December 2017

published in

Immunity

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22 December 2017

volume

5

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22 December 2017

issue

2

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22 December 2017

page(s)

147-161

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22 December 2017

Early events in T-cell maturation

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Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells

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Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection

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Another view of the selective model of thymocyte selection.

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Differentiation potential of subsets of CD4-8- thymocytes

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Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages

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Bcl-2 expression during T-cell development: early loss and late return occur at specific stages of commitment to differentiation and survival

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T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

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Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

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BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

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Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

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Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

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T cell tolerance by clonal elimination in the thymus

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Upregulation of surface markers on dying thymocytes

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Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate

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Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

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7 January 2021

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

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Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway

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7 January 2021

Small cortical thymocytes are subject to positive selection

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Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

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7 January 2021

Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

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7 January 2021

Bclx regulates the survival of double-positive thymocytes

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7 January 2021

The effect of thymus environment on T cell development and tolerance

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7 January 2021

Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.

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7 January 2021

Evidence for a single-niche model of positive selection

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An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

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In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development.

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7 January 2021

Fluorescence-activated cell sorting: theory, experimental optimization, and applications in lymphoid cell biology

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7 January 2021

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

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7 January 2021

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

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7 January 2021

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

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7 January 2021

Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo

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7 January 2021

Thymic emigration: conveyor belts or lucky dips?

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7 January 2021

Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

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7 January 2021

Differentiation of CD3-4-8- thymocytes in short-term thymic stromal cell culture

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7 January 2021

CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

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7 January 2021

The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells

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7 January 2021

Culture of thymic epithelial cells from mice and age-related studies on the growing cells

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7 January 2021

Expression and function of the interleukin 7 receptor in murine lymphocytes

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7 January 2021

T-cell apoptosis detected in situ during positive and negative selection in the thymus

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7 January 2021

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

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7 January 2021

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

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7 January 2021

CD69 expression during selection and maturation of CD4+8+ thymocytes.

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7 January 2021

Small CD4+8+TCRlow thymocytes contain precursors of mature T cells.

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7 January 2021

Immunohistology of T cell differentiation in the thymus of H-Y-specific T cell receptor alpha/beta transgenic mice

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7 January 2021

Development of mature CD8+ thymocytes: selection rather than instruction?

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7 January 2021

In vivo and in vitro clonal deletion of double-positive thymocytes

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7 January 2021

Intracellular signals that mediate thymic negative selection

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7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

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7 January 2021

Positive selection of lymphocytes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980491-4

7 January 2021

CD4/CD8 lineage commitment: back to instruction?

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980491-4

7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

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7 January 2021

Thymus cell migration

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7 January 2021

Thymus cell maturation. Studies on the origin of cortisone-resistant thymic lymphocytes

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7 January 2021

Developmental switches in the immune system

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7 January 2021

Developmental potential of the earliest precursor cells from the adult mouse thymus

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980491-4

7 January 2021

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980491-4

7 January 2021

Positive selection of CD4-CD8+ T cells in the thymus of normal mice

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7 January 2021

10.1016/S1074-7613(00)80491-4

Identifiers

DOI

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22 December 2017

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22 December 2017