(Q46486969)

22 December 2017

title

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells (English)

1 reference

22 December 2017

author name string

Bollag G

1

1 reference

22 December 2017

Clapp DW

2

1 reference

22 December 2017

Shih S

3

1 reference

22 December 2017

Adler F

4

1 reference

22 December 2017

Zhang YY

5

1 reference

22 December 2017

Thompson P

6

1 reference

22 December 2017

Lange BJ

7

1 reference

22 December 2017

Freedman MH

8

1 reference

22 December 2017

McCormick F

9

1 reference

22 December 2017

Jacks T

10

1 reference

22 December 2017

Shannon K

11

1 reference

22 December 2017

language of work or name

English

0 references

publication date

1 February 1996

1 reference

22 December 2017

published in

Nature Genetics

1 reference

22 December 2017

volume

12

1 reference

22 December 2017

page(s)

144-148

1 reference

22 December 2017

issue

2

1 reference

22 December 2017

https://scigraph.springernature.com/pub.10.1038/ng0296-144

exact match

0 references

cites work

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

The GTPase superfamily: conserved structure and molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Signal transduction through small GTPases—A tale of two GAPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Neurofibromatosis type 1 gene mutations in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Myeloid cell transformation by ras-containing murine sarcoma viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Differential regulation of rasGAP and neurofibromatosis gene product activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Interleukin-3 and granulocyte-macrophage colony-stimulating factor receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Stimulation of p21 ras upon T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

Neurofibromatosis and childhood leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Experience in Pediatric Myelodysplastic Syndromes

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Molecular genetic analysis of tumors in von Recklinghausen neurofibromatosis: loss of heterozygosity for chromosome 17.

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Molecular and cytogenetic analysis of tumors in von Recklinghausen neurofibromatosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Mutations in the neurofibromatosis 1 gene in sporadic malignant melanoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Central role of tumour necrosis factor, GM‐CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FNG0296-144

7 January 2021

Identifiers

DOI

10.1038/NG0296-144

1 reference

22 December 2017

PubMed ID

8563751

1 reference

22 December 2017