(Q46502256)

22 December 2017

title

Pharmacokinetics of 5-fluorouracil in patients heterozygous for the IVS14+1G > A mutation in the dihydropyrimidine dehydrogenase gene (English)

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22 December 2017

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A B P van Kuilenburg

1

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22 December 2017

J G Maring

2

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22 December 2017

A Schalhorn

3

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22 December 2017

C Terborg

4

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22 December 2017

H Schmalenberg

5

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22 December 2017

D Behnke

6

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22 December 2017

W Schwabe

7

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22 December 2017

K Jabschinsky

8

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22 December 2017

P Hausler

9

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22 December 2017

publication date

1 June 2008

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22 December 2017

Nucleosides, Nucleotides & Nucleic Acids

published in

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22 December 2017

volume

27

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22 December 2017

issue

6

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22 December 2017

page(s)

692-698

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22 December 2017

Systemic therapy for colorectal cancer

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Capecitabine as adjuvant treatment for stage III colon cancer

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Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

5-Fluorouracil-related severe toxicity: a comparison of different methods for the pretherapeutic detection of dihydropyrimidine dehydrogenase deficiency

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Dose monitoring of 5-fluorouracil in patients with colorectal or head and neck cancer--status of the art.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Reduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial

21 January 2018

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Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity

21 January 2018

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Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Rapid identification of dihydropyrimidine dehydrogenase deficiency by using a novel 2-13C-uracil breath test

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770802145009

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770802145009

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770802145009

Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: high prevalence of the IVS14+1g>a mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770802145009

10.1080/15257770802145009

21 January 2018

Identifiers

DOI

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22 December 2017

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22 December 2017