(Q46520772)

22 December 2017

title

Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer (English)

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22 December 2017

author name string

Susie A Lee

1

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22 December 2017

Coral Ho

2

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22 December 2017

Ritu Roy

3

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22 December 2017

Cynthia Kosinski

4

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22 December 2017

Mohini A Patil

5

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22 December 2017

Aaron D Tward

6

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22 December 2017

Jane Fridlyand

7

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22 December 2017

Xin Chen

8

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22 December 2017

language of work or name

English

0 references

publication date

1 April 2008

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22 December 2017

published in

Hepatology

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22 December 2017

volume

47

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22 December 2017

issue

4

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22 December 2017

page(s)

1200-1210

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22 December 2017

Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis

cites work

1 reference

Low incidence of point mutation of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma.

21 January 2018

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Global cancer statistics in the year 2000.

21 January 2018

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7 January 2021

Genetic mechanisms of hepatocarcinogenesis

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7 January 2021

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

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7 January 2021

Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations

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7 January 2021

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

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7 January 2021

Infrequent point mutations in codons 12 and 61 of ras oncogenes in human hepatocellular carcinomas

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7 January 2021

Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma.

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7 January 2021

Modulation of signalling by Sprouty: a developing story

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7 January 2021

Sprouty and cancer: the first terms report.

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7 January 2021

Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.

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7 January 2021

Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation

1 reference

7 January 2021

Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop

1 reference

7 January 2021

The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer.

1 reference

7 January 2021

Epigenetic inactivation of the human sprouty2 (hSPRY2) homologue in prostate cancer.

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7 January 2021

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

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7 January 2021

Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.

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7 January 2021

Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling.

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7 January 2021

Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma.

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7 January 2021

Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse

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7 January 2021

Distinct pathways of genomic progression to benign and malignant tumors of the liver.

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7 January 2021

An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma

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7 January 2021

Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling

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7 January 2021

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

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7 January 2021

Expression of p27(KIP1) and p21(WAF1/CIP1) in primary hepatocellular carcinoma: clinicopathologic correlation and survival analysis

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7 January 2021

Survivin expression in hepatocellular carcinoma: correlation with proliferation, prognostic parameters, and outcome

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7 January 2021

Disregulation of E-cadherin in transgenic mouse models of liver cancer

1 reference

7 January 2021

Novel endothelial cell markers in hepatocellular carcinoma

1 reference

7 January 2021

Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma

1 reference

7 January 2021

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

1 reference

7 January 2021

New genes involved in cancer identified by retroviral tagging

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7 January 2021

Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

1 reference

7 January 2021

Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.22169

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22 December 2017

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22 December 2017