(Q46543455)

23 December 2017

title

What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations (English)

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23 December 2017

genome-wide association study

main subject

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author

Orestis A. Panagiotou

series ordinal

1

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23 December 2017

John Ioannidis

series ordinal

2

object named as

John P A Ioannidis

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23 December 2017

Genome-Wide Significance Project

series ordinal

3

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23 December 2017

publication date

5 December 2011

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23 December 2017

International Journal of Epidemiology

published in

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23 December 2017

volume

41

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23 December 2017

issue

1

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23 December 2017

page(s)

273-286

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23 December 2017

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

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21 January 2018

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21 January 2018

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Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

21 January 2018

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

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Common variants on chromosome 6p22.1 are associated with schizophrenia

21 January 2018

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Common variants at CD40 and other loci confer risk of rheumatoid arthritis

21 January 2018

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Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

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Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

21 January 2018

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A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The false-positive to false-negative ratio in epidemiologic studies

21 January 2018

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Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

21 January 2018

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Estimating the total number of susceptibility variants underlying complex diseases from genome-wide association studies.

21 January 2018

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Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

21 January 2018

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

21 January 2018

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Genetic associations in large versus small studies: an empirical assessment

21 January 2018

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Common genetic variants for breast cancer: 32 largely refuted candidates and larger prospects

21 January 2018

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Replication validity of genetic association studies

21 January 2018

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Curses--winner's and otherwise--in genetic epidemiology

21 January 2018

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Overcoming the winner's curse: estimating penetrance parameters from case-control data

21 January 2018

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Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer

21 January 2018

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A map of human genome variation from population-scale sequencing

21 January 2018

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Clinical assessment incorporating a personal genome

21 January 2018

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Significance Levels in Genome-Wide Interaction Analysis (GWIA)

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/IJE/DYR178

1 reference

23 December 2017

PubMed ID

22253303

1 reference

23 December 2017