(Q46570455)

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Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification.

scientific article published on 27 June 2005

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15983041%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification (English)

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Europe PubMed Central

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13 January 2020

Escherichia coli

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based on heuristic

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Marta Martinez-vicente

1

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13 January 2020

Magdalena Villarroya

3

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13 January 2020

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Lucía Yim

2

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13 January 2020

Mara Mellado

4

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13 January 2020

Enrique Pérez-Payá

5

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13 January 2020

Glenn R Björk

6

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13 January 2020

M-Eugenia Armengod

7

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13 January 2020

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27 June 2005

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13 January 2020

Journal of Biological Chemistry

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13 January 2020

280

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13 January 2020

35

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13 January 2020

30660-30670

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13 January 2020

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

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21 January 2018

Classification and evolution of P-loop GTPases and related ATPases

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The guanine nucleotide-binding switch in three dimensions

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21 January 2018

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

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21 January 2018

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins

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21 January 2018

GTP hydrolysis mechanism of Ras-like GTPases

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21 January 2018

A built-in arginine finger triggers the self-stimulatory GTPase-activating activity of rho family GTPases.

1 reference

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21 January 2018

Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

The GTPase-activating protein Rap1GAP uses a catalytic asparagine

1 reference

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21 January 2018

RanGAP mediates GTP hydrolysis without an arginine finger

1 reference

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21 January 2018

The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties

1 reference

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21 January 2018

The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.

1 reference

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21 January 2018

MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli

1 reference

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21 January 2018

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA

1 reference

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21 January 2018

Biosynthesis of 5-methylaminomethyl-2-selenouridine, a naturally occurring nucleoside in Escherichia coli tRNA.

1 reference

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21 January 2018

Functional diversity of the rhodanese homology domain: the Escherichia coli ybbB gene encodes a selenophosphate-dependent tRNA 2-selenouridine synthase

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21 January 2018

Selenium-containing tRNAGlu from Clostridium sticklandii: correlation of aminoacylation with selenium content

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21 January 2018

Novel E. coli mutants deficient in biosynthesis of 5-methylaminomethyl-2-thiouridine

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21 January 2018

Isolation and characterization of a selenium metabolism mutant of Salmonella typhimurium

1 reference

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21 January 2018

Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Improvement of reading frame maintenance is a common function for several tRNA modifications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Accurate translation of the genetic code depends on tRNA modified nucleosides.

1 reference

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21 January 2018

The structure of the TrmE GTP-binding protein and its implications for tRNA modification

1 reference

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21 January 2018

Alanine scan mutagenesis of the switch I domain of the Caulobacter crescentus CgtA protein reveals critical amino acids required for in vivo function

1 reference

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21 January 2018

Unexpected structural requirements for GTPase activity of the interferon-induced MxA protein.

1 reference

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21 January 2018

Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

IIGP1, an Interferon-γ-inducible 47-kDa GTPase of the Mouse, Showing Cooperative Enzymatic Activity and GTP-dependent Multimerization

1 reference

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21 January 2018

Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Dynamic properties of the Ras switch I region and its importance for binding to effectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Late events of translation initiation in bacteria: a kinetic analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503223200

21 January 2018

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

1 reference

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21 January 2018

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

1 reference

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21 January 2018

Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism

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21 January 2018

MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase

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21 January 2018

MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae.

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21 January 2018

A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation

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21 January 2018

Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12 S rRNA A1555G mutation

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21 January 2018

Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases

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21 January 2018

X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding

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21 January 2018

Insights into the decoding mechanism from recent ribosome structures

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21 January 2018

Elongation factors in protein biosynthesis

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21 January 2018

EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome

1 reference

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21 January 2018

Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation

1 reference

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21 January 2018

Peptidyl-tRNA regulates the GTPase activity of translation factors

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Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA

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Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease

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Wobble modification defect suppresses translational activity of tRNAs with MERRF and MELAS mutations

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21 January 2018

Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases.

1 reference

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Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease

1 reference

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21 January 2018

Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease

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21 January 2018

The arginine finger strikes again

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M503223200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15983041%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15983041%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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