(Q46578172)

23 December 2017

title

Sticking together the Crumbs - an unexpected function for an old friend (English)

1 reference

23 December 2017

author

Barry James Thompson

series ordinal

1

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23 December 2017

Katja Röper

object named as

Katja Röper

series ordinal

3

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Franck Pichaud

object named as

Franck Pichaud

series ordinal

2

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publication date

1 May 2013

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23 December 2017

Nature Reviews Molecular Cell Biology

published in

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23 December 2017

volume

14

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23 December 2017

issue

5

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23 December 2017

page(s)

307-314

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23 December 2017

https://scigraph.springernature.com/pub.10.1038/nrm3568

exact match

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cites work

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

1 reference

CRUMBS is involved in the control of apical protein targeting during Drosophila epithelial development.

21 January 2018

1 reference

The Crumbs complex: from epithelial-cell polarity to retinal degeneration

21 January 2018

1 reference

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

21 January 2018

1 reference

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

21 January 2018

1 reference

oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo.

21 January 2018

1 reference

The apical polarity protein network in Drosophila epithelial cells: regulation of polarity, junctions, morphogenesis, cell growth, and survival

21 January 2018

1 reference

Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains

21 January 2018

1 reference

Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium

21 January 2018

1 reference

Anisotropy of Crumbs and aPKC drives myosin cable assembly during tube formation

21 January 2018

1 reference

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.

21 January 2018

1 reference

A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila.

21 January 2018

1 reference

CRB1 has a cytoplasmic domain that is functionally conserved between human and Drosophila

21 January 2018

1 reference

Leber congenital amaurosis and retinitis pigmentosa with Coats-like exudative vasculopathy are associated with mutations in the crumbs homologue 1 (CRB1) gene

21 January 2018

1 reference

aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

21 January 2018

1 reference

Crumbs/DaPKC-dependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling

21 January 2018

1 reference

Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia

21 January 2018

1 reference

Mutations in the CRB1 gene cause Leber congenital amaurosis

21 January 2018

1 reference

Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene

21 January 2018

1 reference

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

21 January 2018

1 reference

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres

21 January 2018

1 reference

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

21 January 2018

1 reference

Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death

21 January 2018

1 reference

Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded

21 January 2018

1 reference

Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

21 January 2018

1 reference

The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded

21 January 2018

1 reference

The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

21 January 2018

1 reference

Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of gamma-secretase activity

21 January 2018

1 reference

Crumbs is required to achieve proper organ size control during Drosophila head development

21 January 2018

1 reference

Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells.

21 January 2018

1 reference

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

21 January 2018

1 reference

Fosmid-based structure-function analysis reveals functionally distinct domains in the cytoplasmic domain of Drosophila crumbs

21 January 2018

1 reference

Integrated activity of PDZ protein complexes regulates epithelial polarity

21 January 2018

1 reference

Asymmetric cell division: recent developments and their implications for tumour biology

21 January 2018

1 reference

Crumbs stabilises epithelial polarity during tissue remodelling

21 January 2018

1 reference

Patterned gene expression directs bipolar planar polarity in Drosophila

21 January 2018

1 reference

Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation

21 January 2018

1 reference

CRB1 mutation spectrum in inherited retinal dystrophies

21 January 2018

1 reference

A role for the extracellular domain of Crumbs in morphogenesis of Drosophila photoreceptor cells

21 January 2018

1 reference

Cdc42 and Par proteins stabilize dynamic adherens junctions in the Drosophila neuroectoderm through regulation of apical endocytosis

21 January 2018

1 reference

Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries

21 January 2018

1 reference

Cell biology: a new view of photoreceptors

21 January 2018

1 reference

The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster

21 January 2018

1 reference

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

1 reference

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

1 reference

Endocytic internalization routes required for delta/notch signaling

21 January 2018

1 reference

Overexpression of human CRB1 or related isoforms, CRB2 and CRB3, does not regulate the human presenilin complex in culture cells

21 January 2018

1 reference

Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex

21 January 2018

1 reference

DE-Cadherin is required for intercellular motility during Drosophila oogenesis

21 January 2018

1 reference

Requirement for Par-6 and Bazooka in Drosophila border cell migration

21 January 2018

1 reference

Retromer controls epithelial cell polarity by trafficking the apical determinant Crumbs

21 January 2018

1 reference

Adherens junctions: from molecules to morphogenesis

21 January 2018

1 reference

Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling

21 January 2018

1 reference

The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway

21 January 2018

1 reference

Differential adhesion and actomyosin cable collaborate to drive Echinoid-mediated cell sorting

21 January 2018

1 reference

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : II. Zygotic loci on the third chromosome

21 January 2018

1 reference

The Drosophila genes crumbs and stardust are involved in the biogenesis of adherens junctions.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23609509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A functional role of the extracellular domain of Crumbs in cell architecture and apicobasal polarity.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23609509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM3568

1 reference

23 December 2017

1 reference

23 December 2017