(Q46605596)

23 December 2017

title

Redundant role for Zap70 in B cell development and activation (English)

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23 December 2017

author name string

Farnaz Fallah-Arani

1

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23 December 2017

Edina Schweighoffer

2

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23 December 2017

Lesley Vanes

3

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23 December 2017

Victor L J Tybulewicz

4

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23 December 2017

language of work or name

English

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publication date

1 June 2008

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23 December 2017

European Journal of Immunology

published in

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23 December 2017

volume

38

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23 December 2017

issue

6

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23 December 2017

page(s)

1721-1733

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23 December 2017

The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils

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Tyrosine kinase SYK: essential functions for immunoreceptor signalling

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7 January 2021

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

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7 January 2021

Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells

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7 January 2021

GPVI and integrin alphaIIb beta3 signaling in platelets

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7 January 2021

Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins

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7 January 2021

NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.

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7 January 2021

Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

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7 January 2021

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

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7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

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7 January 2021

Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool

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7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

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7 January 2021

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

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7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

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7 January 2021

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

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7 January 2021

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

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7 January 2021

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

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7 January 2021

Chronic lymphocytic leukemia: revelations from the B-cell receptor.

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7 January 2021

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

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7 January 2021

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

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7 January 2021

ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia

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7 January 2021

ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells.

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7 January 2021

Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion.

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7 January 2021

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

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7 January 2021

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

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7 January 2021

ZAP-70 is expressed by normal and malignant human B-cell subsets of different maturational stage.

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7 January 2021

Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase

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https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

1 reference

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7 January 2021

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

Distinct roles for Syk and ZAP-70 during early thymocyte development

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https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation

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https://api.crossref.org/works/10.1002%2FEJI.200738026

7 January 2021

Plat-E: an efficient and stable system for transient packaging of retroviruses

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7 January 2021

TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity

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7 January 2021

Identifiers

DOI

10.1002/EJI.200738026

1 reference

23 December 2017

1 reference

23 December 2017