(Q46622731)

23 December 2017

title

Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes (English)

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23 December 2017

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23 December 2017

publication date

17 December 2015

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23 December 2017

published in

The Plant Journal

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23 December 2017

volume

87

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23 December 2017

issue

1

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23 December 2017

page(s)

5-15

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23 December 2017

describes a project that uses

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Rewriting the blueprint of life by synthetic genomics and genome engineering

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Enabling plant synthetic biology through genome engineering

21 January 2018

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DNA replicons for plant genome engineering.

21 January 2018

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Editing plant genomes with CRISPR/Cas9.

21 January 2018

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Promises and pitfalls of synthetic chromosomes in plants

21 January 2018

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Breaking the code of DNA binding specificity of TAL-type III effectors

21 January 2018

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Targeted Integration of T-DNA into the Tobacco Genome at Double-Stranded Breaks: New Insights on the Mechanism of T-DNA Integration

21 January 2018

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

21 January 2018

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Genome elimination: translating basic research into a future tool for plant breeding

21 January 2018

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Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease

21 January 2018

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Genome editing. The new frontier of genome engineering with CRISPR-Cas9

21 January 2018

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Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice

21 January 2018

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21 January 2018

In planta gene targeting

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Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana.

21 January 2018

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Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

21 January 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

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In vivo modification of a maize engineered minichromosome.

21 January 2018

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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

21 January 2018

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Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome

21 January 2018

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

21 January 2018

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Chromatin and development: a special issue.

21 January 2018

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Precise plant breeding using new genome editing techniques: opportunities, safety and regulation in the EU.

21 January 2018

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Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family

21 January 2018

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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

21 January 2018

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Development and applications of CRISPR-Cas9 for genome engineering

21 January 2018

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Zinc finger artificial transcription factor-based nearest inactive analogue/nearest active analogue strategy used for the identification of plant genes controlling homologous recombination.

21 January 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

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Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta

21 January 2018

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Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity

21 January 2018

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CRISPR transcriptional repression devices and layered circuits in mammalian cells

21 January 2018

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Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 January 2018

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Species-specific double-strand break repair and genome evolution in plants

21 January 2018

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Engineered CRISPR-Cas9 nucleases with altered PAM specificities

21 January 2018

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DNA recombination in somatic plant cells: mechanisms and evolutionary consequences

21 January 2018

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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

21 January 2018

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Strategies for precision modulation of gene expression by epigenome editing: an overview

21 January 2018

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21 January 2018

CRISPR, the disruptor

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Designed nucleases for targeted genome editing

21 January 2018

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Employing libraries of zinc finger artificial transcription factors to screen for homologous recombination mutants in Arabidopsis

21 January 2018

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21 January 2018

Plant synthetic biology

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Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

21 January 2018

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Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

21 January 2018

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The role of CRISPR-Cas systems in virulence of pathogenic bacteria

21 January 2018

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A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation

21 January 2018

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A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants

21 January 2018

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Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

21 January 2018

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Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives

21 January 2018

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

21 January 2018

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A chimeric AtMYB23 repressor induces hairy roots, elongation of leaves and stems, and inhibition of the deposition of mucilage on seed coats in Arabidopsis

21 January 2018

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Two unlinked double-strand breaks can induce reciprocal exchanges in plant genomes via homologous recombination and nonhomologous end joining

21 January 2018

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Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors

21 January 2018

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Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9.

21 January 2018

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Targeted stimulation of meiotic recombination.

21 January 2018

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Zinc finger nuclease-mediated transgene deletion

21 January 2018

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RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors.

21 January 2018

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Gene targeting in plants: 25 years later

21 January 2018

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Synthetic nucleases for genome engineering in plants: prospects for a bright future

21 January 2018

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Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination

21 January 2018

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Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases

21 January 2018

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Creating Designed Zinc-Finger Nucleases with Minimal Cytotoxicity

21 January 2018

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Intergeneric transfer of a partial genome and direct production of monosomic addition plants by microprotoplast fusion

21 January 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

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In vivo genome editing using Staphylococcus aureus Cas9

21 January 2018

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Zinc finger phage: affinity selection of fingers with new DNA-binding specificities

21 January 2018

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

21 January 2018

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Capture of genomic and T-DNA sequences during double-strand break repair in somatic plant cells

21 January 2018

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CRISPR/Cas9-mediated genome editing and gene replacement in plants: Transitioning from lab to field.

21 January 2018

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Synthetic biology in plastids.

21 January 2018

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The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny

21 January 2018

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Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut.

21 January 2018

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Precise genome modification in the crop species Zea mays using zinc-finger nucleases

21 January 2018

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Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

21 January 2018

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Gene stacking by recombinases

21 January 2018

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Regulation of RNA polymerase II activation by histone acetylation in single living cells.

21 January 2018

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Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophilus and Staphylococcus aureus

21 January 2018

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Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

21 January 2018

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Targeted mutagenesis in soybean using the CRISPR-Cas9 system

21 January 2018

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Targeted Mutagenesis, Precise Gene Editing, and Site-Specific Gene Insertion in Maize Using Cas9 and Guide RNA.

21 January 2018

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Induction of telomere-mediated chromosomal truncation and stability of truncated chromosomes in Arabidopsis thaliana.

21 January 2018

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Artificial transcription factor-mediated regulation of gene expression

21 January 2018

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High-frequency modification of plant genes using engineered zinc-finger nucleases

21 January 2018

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Plant genome engineering with sequence-specific nucleases

21 January 2018

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Use of designer nucleases for targeted gene and genome editing in plants

21 January 2018

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Nonhomologous end joining-mediated gene replacement in plant cells.

21 January 2018

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Detection of an inversion in the Ty-2 region between S. lycopersicum and S. habrochaites by a combination of de novo genome assembly and BAC cloning

21 January 2018

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DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins

21 January 2018

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High-frequency homologous recombination in plants mediated by zinc-finger nucleases

21 January 2018

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Progress of chromosome engineering mediated by asymmetric somatic hybridization

21 January 2018

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Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system.

21 January 2018

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Construction of rice mini-chromosomes by telomere-mediated chromosomal truncation

21 January 2018

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DNA methylation epigenetically silences crossover hot spots and controls chromosomal domains of meiotic recombination in Arabidopsis

21 January 2018

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Telomere-mediated chromosomal truncation in maize

21 January 2018

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Plant artificial chromosome technology and its potential application in genetic engineering

21 January 2018

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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

21 January 2018

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Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice

21 January 2018

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Emerging tools for synthetic biology in plants

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/TPJ.13100

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23 December 2017

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23 December 2017