(Q26787105)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26369767%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Designed nucleases for targeted genome editing (English)

1 reference

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24 February 2020

1

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24 February 2020

author name string

Jae-Hee Chung

2

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24 February 2020

Ho Min Kim

3

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24 February 2020

Dong-Wook Kim

4

1 reference

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24 February 2020

Hyongbum Kim

5

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24 February 2020

language of work or name

English

0 references

publication date

15 September 2015

1 reference

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Plant Biotechnology Journal

24 February 2020

published in

1 reference

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24 February 2020

volume

14

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24 February 2020

issue

2

1 reference

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24 February 2020

page(s)

448-462

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26369767%20AND%20SRC:MED&resulttype=core&format=json

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

24 February 2020

cites work

1 reference

Human zinc fingers as building blocks in the construction of artificial transcription factors.

21 January 2018

1 reference

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

21 January 2018

1 reference

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

21 January 2018

1 reference

Highly active zinc-finger nucleases by extended modular assembly

21 January 2018

1 reference

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

21 January 2018

1 reference

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

21 January 2018

1 reference

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

21 January 2018

1 reference

FokI dimerization is required for DNA cleavage

21 January 2018

1 reference

The CRISPR/Cas9 system for plant genome editing and beyond

21 January 2018

1 reference

Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers

21 January 2018

1 reference

Chromosomal translocations induced at specified loci in human stem cells.

21 January 2018

1 reference

Efficient TALEN-mediated gene knockout in livestock

21 January 2018

1 reference

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

21 January 2018

1 reference

High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

21 January 2018

1 reference

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

21 January 2018

1 reference

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

21 January 2018

1 reference

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

21 January 2018

1 reference

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

21 January 2018

1 reference

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

21 January 2018

1 reference

Targeted integration in rat and mouse embryos with zinc-finger nucleases

21 January 2018

1 reference

DNA nicks promote efficient and safe targeted gene correction

21 January 2018

1 reference

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

21 January 2018

1 reference

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

21 January 2018

1 reference

Redesigning the DNA-binding specificity of a zinc finger protein: a data base-guided approach

21 January 2018

1 reference

Mammalian base excision repair: the forgotten archangel

21 January 2018

1 reference

Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs

21 January 2018

1 reference

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

21 January 2018

1 reference

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells

21 January 2018

1 reference

Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions

21 January 2018

1 reference

Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana.

21 January 2018

1 reference

Saturation editing of genomic regions by multiplex homology-directed repair

21 January 2018

1 reference

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

21 January 2018

1 reference

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

21 January 2018

1 reference

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

1 reference

An unbiased genome-wide analysis of zinc-finger nuclease specificity

21 January 2018

1 reference

Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats

21 January 2018

1 reference

Targeted gene knockout by direct delivery of zinc-finger nuclease proteins

21 January 2018

1 reference

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

21 January 2018

1 reference

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

21 January 2018

1 reference

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

21 January 2018

1 reference

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

21 January 2018

1 reference

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

21 January 2018

1 reference

An optimized two-finger archive for ZFN-mediated gene targeting

21 January 2018

1 reference

Targeted chromosomal deletions and inversions in zebrafish

21 January 2018

1 reference

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

1 reference

E-TALEN: a web tool to design TALENs for genome engineering.

21 January 2018

1 reference

E-CRISP: fast CRISPR target site identification.

21 January 2018

1 reference

Genetic engineering of human pluripotent cells using TALE nucleases

21 January 2018

1 reference

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

21 January 2018

1 reference

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

21 January 2018

1 reference

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

Efficient genome editing in zebrafish using a CRISPR-Cas system

21 January 2018

1 reference

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

21 January 2018

1 reference

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

RNA-programmed genome editing in human cells

21 January 2018

1 reference

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

21 January 2018

1 reference

A guide to genome engineering with programmable nucleases

21 January 2018

1 reference

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 January 2018

1 reference

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

21 January 2018

1 reference

Genome editing with modularly assembled zinc-finger nucleases

21 January 2018

1 reference

Precision genome engineering with programmable DNA-nicking enzymes

21 January 2018

1 reference

A library of TAL effector nucleases spanning the human genome

21 January 2018

1 reference

TALEN-based knockout library for human microRNAs

21 January 2018

1 reference

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

21 January 2018

1 reference

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

21 January 2018

1 reference

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

21 January 2018

1 reference

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

21 January 2018

1 reference

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

21 January 2018

1 reference

Insights into effective RNAi gained from large-scale siRNA validation screening

21 January 2018

1 reference

Modeling of the human alveolar rhabdomyosarcoma Pax3-Foxo1 chromosome translocation in mouse myoblasts using CRISPR-Cas9 nuclease

21 January 2018

1 reference

Targeted chromosomal deletions in human cells using zinc finger nucleases

21 January 2018

1 reference

Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases

21 January 2018

1 reference

In vivo genome editing restores haemostasis in a mouse model of haemophilia

21 January 2018

1 reference

Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.

21 January 2018

1 reference

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems.

21 January 2018

1 reference

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

Ageing, repetitive genomes and DNA damage

21 January 2018

1 reference

Mechanism and regulation of human non-homologous DNA end-joining

21 January 2018

1 reference

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

21 January 2018

1 reference

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

21 January 2018

1 reference

Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays

21 January 2018

1 reference

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

21 January 2018

1 reference

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

21 January 2018

1 reference

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

21 January 2018

1 reference

RNA-guided human genome engineering via Cas9

21 January 2018

1 reference

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

21 January 2018

1 reference

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

21 January 2018

1 reference

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

21 January 2018

1 reference

An improved zinc-finger nuclease architecture for highly specific genome editing

21 January 2018

1 reference

A TALE nuclease architecture for efficient genome editing

21 January 2018

1 reference

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

21 January 2018

1 reference

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

21 January 2018

1 reference

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

21 January 2018

1 reference

Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

21 January 2018

1 reference

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

21 January 2018

1 reference

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

21 January 2018

1 reference

Zinc finger nuclease-mediated transgene deletion.

21 January 2018

1 reference

Chimeric nucleases stimulate gene targeting in human cells

21 January 2018

1 reference

Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease

21 January 2018

1 reference

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

21 January 2018

1 reference

Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases

21 January 2018

1 reference

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA.

21 January 2018

1 reference

Unexpected failure rates for modular assembly of engineered zinc fingers

21 January 2018

1 reference

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

21 January 2018

1 reference

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

1 reference

In vivo genome editing using Staphylococcus aureus Cas9

21 January 2018

1 reference

Zinc finger phage: affinity selection of fingers with new DNA-binding specificities

21 January 2018

1 reference

FLASH assembly of TALENs for high-throughput genome editing

21 January 2018

1 reference

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

21 January 2018

1 reference

Capture of genomic and T-DNA sequences during double-strand break repair in somatic plant cells

21 January 2018

1 reference

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

21 January 2018

1 reference

The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

21 January 2018

1 reference

Holliday junction processing enzymes as guardians of genome stability

21 January 2018

1 reference

The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny.

21 January 2018

1 reference

A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes

21 January 2018

1 reference

Genome engineering at the dawn of the golden age.

21 January 2018

1 reference

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

21 January 2018

1 reference

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

21 January 2018

1 reference

Protospacer recognition motifs: mixed identities and functional diversity

21 January 2018

1 reference

Genome-scale CRISPR-Cas9 knockout screening in human cells

21 January 2018

1 reference

Targeted genome modification of crop plants using a CRISPR-Cas system.

21 January 2018

1 reference

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

21 January 2018

1 reference

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

21 January 2018

1 reference

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

21 January 2018

1 reference

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

21 January 2018

1 reference

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

21 January 2018

1 reference

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

21 January 2018

1 reference

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

21 January 2018

1 reference

Structure of FokI has implications for DNA cleavage

21 January 2018

1 reference

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

21 January 2018

1 reference

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

21 January 2018

1 reference

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors.

21 January 2018

1 reference

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

21 January 2018

1 reference

DNA recognition by Cys2His2 zinc finger proteins

21 January 2018

1 reference

Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish.

21 January 2018

1 reference

Genome-wide prediction of highly specific guide RNA spacers for CRISPR-Cas9-mediated genome editing in model plants and major crops.

21 January 2018

1 reference

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system.

21 January 2018

1 reference

Optimization of scarless human stem cell genome editing

21 January 2018

1 reference

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

21 January 2018

1 reference

Small molecules enhance CRISPR genome editing in pluripotent stem cells.

21 January 2018

1 reference

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds

21 January 2018

1 reference

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

21 January 2018

1 reference

Optical control of mammalian endogenous transcription and epigenetic states

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Safe harbours for the integration of new DNA in the human genome

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1111/PBI.12465

2 references

Consolidated OpenCitations Corpus – April 2017

3583807

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26369767%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

3583807

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3583807