(Q35621362)

9 August 2017

1 reference

title

Ageing, repetitive genomes and DNA damage (English)

1 reference

9 August 2017

0 references

Michael R Lieber

1

1 reference

PubMed ID

14708011

9 August 2017

Zarir E Karanjawala

series ordinal

2

1 reference

9 August 2017

1 January 2004

1 reference

Nature Reviews Molecular Cell Biology

9 August 2017

1 reference

9 August 2017

5

1 reference

9 August 2017

69-75

1 reference

9 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/nrm1281

9 August 2017

0 references

cites work

Rate of generation of oxidative stress-related damage and animal longevity

1 reference

The free radical theory of aging matures

31 March 2020

1 reference

Aging and genome maintenance: lessons from the mouse?

31 March 2020

1 reference

Genetics and the specificity of the aging process

31 March 2020

1 reference

Evolutionary medicine: from dwarf model systems to healthy centenarians?

31 March 2020

1 reference

The endocrine regulation of aging by insulin-like signals

31 March 2020

1 reference

Living fast, dying when? The link between aging and energetics

31 March 2020

1 reference

Mechanisms of aging: an appraisal of the oxidative stress hypothesis

31 March 2020

1 reference

Aging mechanisms in fruit files

31 March 2020

1 reference

Lamin a truncation in Hutchinson-Gilford progeria.

31 March 2020

1 reference

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

31 March 2020

1 reference

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

31 March 2020

1 reference

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

31 March 2020

1 reference

Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart

31 March 2020

1 reference

Comparative biology of aging in birds: an update

31 March 2020

1 reference

Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials.

31 March 2020

1 reference

DNA damage and oxygen radical toxicity

31 March 2020

1 reference

How oxygen damages microbes: oxygen tolerance and obligate anaerobiosis

31 March 2020

1 reference

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

31 March 2020

1 reference

Does oxidative damage to DNA increase with age?

31 March 2020

1 reference

Mutational fingerprints of aging

31 March 2020

1 reference

Hydroperoxide metabolism in mammalian organs

31 March 2020

1 reference

Mechanism and regulation of human non-homologous DNA end-joining

31 March 2020

1 reference

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

31 March 2020

1 reference

Break-induced replication: a review and an example in budding yeast

31 March 2020

1 reference

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

31 March 2020

1 reference

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

31 March 2020

1 reference

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

31 March 2020

1 reference

Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants

31 March 2020

1 reference

DNA-PKcs is critical for telomere capping

31 March 2020

1 reference

Deletion of Ku86 causes early onset of senescence in mice

31 March 2020

1 reference

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

31 March 2020

1 reference

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

31 March 2020

1 reference

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

31 March 2020

1 reference

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

31 March 2020

1 reference

Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice

31 March 2020

1 reference

Bidirectional gene organization: a common architectural feature of the human genome.

31 March 2020

1 reference

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

31 March 2020

1 reference

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

31 March 2020

1 reference

Loss of Werner syndrome protein function promotes aberrant mitotic recombination

31 March 2020

1 reference

Homologous recombination resolution defect in werner syndrome

31 March 2020

1 reference

Functional interaction between Ku and the werner syndrome protein in DNA end processing

31 March 2020

1 reference

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

31 March 2020

1 reference

Life at the edge: the nuclear envelope and human disease

31 March 2020

1 reference

Aneuploidy analysis in fibroblasts of human premature aging syndromes by FISH during in vitro cellular aging

31 March 2020

1 reference

Lessons from human progeroid syndromes

31 March 2020

1 reference

Recombination and joining: different means to the same ends

31 March 2020

1 reference

Chromosomal stability and the DNA double-stranded break connection

31 March 2020

1 reference

Oxidative biochemical markers; clues to understanding aging in long-lived species

31 March 2020

1 reference

Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential

31 March 2020

1 reference

Origin and evolution of avian microchromosomes

31 March 2020

1 reference

How bats achieve a small C-value: frequency of repetitive DNA in Macrotus

31 March 2020

1 reference

Increased ratio of targeted to random integration after transfection of chicken B cell lines.

31 March 2020

1 reference

Exceptional cellular resistance to oxidative damage in long-lived birds requires active gene expression

31 March 2020

1 reference

Redox regulation and signaling lipids in mitochondrial apoptosis

31 March 2020

1 reference

The aging-disease dichotomy: true or false?

31 March 2020

1 reference

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

31 March 2020

1 reference

Aging: a theory based on free radical and radiation chemistry

31 March 2020

1 reference

DNA damage as the primary cause of aging

31 March 2020

1 reference

The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants

31 March 2020

1 reference

Mitochondrial diseases in man and mouse

31 March 2020

1 reference

Genome dynamics in aging mice

31 March 2020

1 reference

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

31 March 2020

1 reference

Ku80‐ and DNA ligase IV‐deficient plants are sensitive to ionizing radiation and defective in T‐DNA integration

31 March 2020

1 reference

Molecular views of recombination proteins and their control

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM1281

1 reference

PubMed ID

14708011

Dimensions Publication ID

9 August 2017

0 references

1 reference

PubMed ID

14708011