(Q34257442)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Toni Cathomen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

9

J Keith Joung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

Cherie L Ramirez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Michael T Certo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Claudio Mussolino

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Mathew J Goodwin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Anton P McCaffrey

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Andrew M Scharenberg

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

language of work or name

English

0 references

publication date

28 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

5560-5568

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

24 January 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

TAL effectors: customizable proteins for DNA targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

DNA nicks promote efficient and safe targeted gene correction

6 July 2018

1 reference

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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

6 July 2018

1 reference

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An unbiased genome-wide analysis of zinc-finger nuclease specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Tracking genome engineering outcome at individual DNA breakpoints

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Cell cycle-dependent induction of homologous recombination by a tightly regulated I-SceI fusion protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Zinc-finger nuclease based genome surgery: it's all about specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs.

6 July 2018

1 reference

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Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays

6 July 2018

1 reference

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Mechanisms of double-strand break repair in somatic mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Stimulation of homology-directed gene targeting at an endogenous human locus by a nicking endonuclease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Chromosomal translocations induced at specified loci in human stem cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

High-frequency modification of plant genes using engineered zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

An improved zinc-finger nuclease architecture for highly specific genome editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Efficient gene targeting in Drosophila with zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Alternative pathways for the repair of RAG-induced DNA breaks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

DNAWorks: an automated method for designing oligonucleotides for PCR-based gene synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

FokI dimerization is required for DNA cleavage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Single amino acid substitutions uncouple the DNA binding and strand scission activities of Fok I endonuclease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

A general model for genetic recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384306

Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair.

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS179

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS179

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS179

Custom zinc-finger nucleases for use in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS179

A mechanism for gene conversion in fungi

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22373919

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKS179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373919%20AND%20SRC:MED&resulttype=core&format=json