(Q34205743)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Claudio Mussolino

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Robert Morbitzer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Fabienne Lütge

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Nadine Dannemann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Thomas Lahaye

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

3 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

9283-9293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

9 February 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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Assembly of custom TALE-type DNA binding domains by modular cloning

5 July 2018

1 reference

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De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

5 July 2018

1 reference

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Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

5 July 2018

1 reference

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Zinc-finger nuclease based genome surgery: it's all about specificity

5 July 2018

1 reference

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A TALE nuclease architecture for efficient genome editing

5 July 2018

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Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

5 July 2018

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Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

5 July 2018

1 reference

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Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

5 July 2018

1 reference

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Genome editing with engineered zinc finger nucleases

5 July 2018

1 reference

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Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

5 July 2018

1 reference

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

5 July 2018

1 reference

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Quantification of zinc finger nuclease-associated toxicity

5 July 2018

1 reference

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Targeting DNA double-strand breaks with TAL effector nucleases

5 July 2018

1 reference

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Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

5 July 2018

1 reference

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TAL effectors: finding plant genes for disease and defense

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Genome editing with modularly assembled zinc-finger nucleases

5 July 2018

1 reference

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Targeted chromosomal deletions in human cells using zinc finger nucleases

5 July 2018

1 reference

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Breaking the code of DNA binding specificity of TAL-type III effectors

5 July 2018

1 reference

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A simple cipher governs DNA recognition by TAL effectors

5 July 2018

1 reference

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

5 July 2018

1 reference

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Knockout rats via embryo microinjection of zinc-finger nucleases

5 July 2018

1 reference

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Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

High-frequency modification of plant genes using engineered zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity

5 July 2018

1 reference

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

5 July 2018

1 reference

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Zinc-finger nucleases: the next generation emerges

5 July 2018

1 reference

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Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

5 July 2018

1 reference

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Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

5 July 2018

1 reference

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Unexpected failure rates for modular assembly of engineered zinc fingers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

An improved zinc-finger nuclease architecture for highly specific genome editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Structure of the multimodular endonuclease FokI bound to DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241638

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKR597

Custom zinc-finger nucleases for use in human cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKR597

Recognition of AvrBs3-like proteins is mediated by specific binding to promoters of matching pepper Bs3 alleles.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKR597

Preassembled zinc-finger arrays for rapid construction of ZFNs

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21813459

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKR597

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference