(Q34124290)

31 July 2017

title

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo (English)

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31 July 2017

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8

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31 July 2017

Philip D Gregory

9

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Gay M. Crooks

7

object named as

Gay M Crooks

1 reference

31 July 2017

Nathalia Holt

1

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31 July 2017

Jianbin Wang

2

1 reference

31 July 2017

Kenneth Kim

3

1 reference

31 July 2017

Geoffrey Friedman

4

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31 July 2017

Xingchao Wang

5

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31 July 2017

Vanessa Taupin

6

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31 July 2017

Michael C Holmes

10

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31 July 2017

Paula M Cannon

11

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31 July 2017

publication date

2 July 2010

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31 July 2017

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31 July 2017

volume

28

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31 July 2017

issue

8

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31 July 2017

page(s)

839-847

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IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivo

31 July 2017

cites work

1 reference

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CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells

5 July 2018

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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

5 July 2018

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Stable transgene expression in primitive human CD34+ hematopoietic stem/progenitor cells, using the Sleeping Beauty transposon system

5 July 2018

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Transplantation of selected or transgenic blood stem cells - a future treatment for HIV/AIDS?

5 July 2018

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Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis

5 July 2018

1 reference

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Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy

5 July 2018

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The gastrointestinal tract and AIDS pathogenesis

5 July 2018

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Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

5 July 2018

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The challenge of finding a cure for HIV infection

5 July 2018

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Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

5 July 2018

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

5 July 2018

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Novel targets for antiretroviral therapy: clinical progress to date

5 July 2018

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T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

5 July 2018

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CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual

5 July 2018

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Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

5 July 2018

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Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

5 July 2018

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Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

5 July 2018

1 reference

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Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Mapping resistance to the CCR5 co-receptor antagonist vicriviroc using heterologous chimeric HIV-1 envelope genes reveals key determinants in the C2-V5 domain of gp120.

5 July 2018

1 reference

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Immune activation and inflammation in HIV-1 infection: causes and consequences

5 July 2018

1 reference

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Genetic therapies against HIV.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-gamma c-/- (RAG-hu) mouse model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Stable gene transfer to human CD34(+) hematopoietic cells using the Sleeping Beauty transposon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

5 July 2018

1 reference

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Can gene delivery close the door to HIV-1 entry after escape?

5 July 2018

1 reference

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Differential usage of non-homologous end-joining and homologous recombination in double strand break repair

5 July 2018

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Immunopathogenesis of acute AIDS virus infection

5 July 2018

1 reference

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T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery.

5 July 2018

1 reference

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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

5 July 2018

1 reference

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Distribution of health care expenditures for HIV-infected patients

5 July 2018

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HIV disease: fallout from a mucosal catastrophe?

5 July 2018

1 reference

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CCR5 deficiency increases risk of symptomatic West Nile virus infection

5 July 2018

1 reference

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Transfer and evaluation of an automated, low-cost real-time reverse transcription-PCR test for diagnosis and monitoring of human immunodeficiency virus type 1 infection in a West African resource-limited setting

5 July 2018

1 reference

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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

5 July 2018

1 reference

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

R5 human immunodeficiency virus type 1 infection of fetal thymic organ culture induces cytokine and CCR5 expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

In vivo reversion to normal of inherited mutations in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

The mucosal immune system: primary target for HIV infection and AIDS.

5 July 2018

1 reference

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Acute human immunodeficiency virus type 1 infection

5 July 2018

1 reference

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Genetic manipulation of genomes with rare-cutting endonucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

5 July 2018

1 reference

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

5 July 2018

1 reference

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Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry

5 July 2018

1 reference

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Transgenic enrichment of cardiomyocytes from human embryonic stem cells

5 July 2018

1 reference

Impact of inversion of the CD4/CD8 ratio on the natural history of HIV-1 infection.

21 January 2018

1 reference

A mechanism for the impaired IFN-gamma production in C-C chemokine receptor 2 (CCR2) knockout mice: role of CCR2 in linking the innate and adaptive immune responses.

21 January 2018

1 reference

Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system

21 January 2018

1 reference

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Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

28 October 2018

1 reference

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Primary genotypic resistance of HIV-1 to CCR5 antagonists in CCR5 antagonist treatment-naive patients

28 October 2018

1 reference

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HIV-1 coreceptor usage and CXCR4-specific viral load predict clinical disease progression during combination antiretroviral therapy.

28 October 2018

1 reference

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Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells

28 October 2018

1 reference

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CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis.

28 October 2018

1 reference

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Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

28 October 2018

1 reference

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Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Autologous stem cell transplantation for HIV-associated lymphoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Effect of HIV-1 infection on lymphocyte proliferation in gut-associated lymphoid tissue

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Natural History of HIV-1 Cell-Free Viremia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080757

Atypical X-Linked Severe Combined Immunodeficiency Due to Possible Spontaneous Reversion of the Genetic Defect in T Cells

28 October 2018

1 reference

12 December 2020

CC chemokine receptor 5 cell-surface expression in relation to CC chemokine receptor 5 genotype and the clinical course of HIV-1 infection

1 reference

12 December 2020

Revertant somatic mosaicism in the Wiskott-Aldrich syndrome

1 reference

12 December 2020

Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency

1 reference

12 December 2020

CCR2 chemokine receptor and AIDS progression

1 reference

12 December 2020

HIV-1 infection in an individual homozygous for the CCR5 deletion allele

1 reference

12 December 2020

The geographic spread of the CCR5 Delta32 HIV-resistance allele

1 reference

7 January 2021

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