(Q39500874)

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Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

author name string

Eva-Maria Händel

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Stephen Alwin

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

publication date

11 November 2008

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Molecular Therapy

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

17

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

104-111

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

1 reference

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12 September 2017

Zinc-finger nucleases: the next generation emerges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Unexpected failure rates for modular assembly of engineered zinc fingers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

1 reference

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

An improved zinc-finger nuclease architecture for highly specific genome editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Efficient gene targeting in Drosophila with zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Genetic steps of mammalian homologous repair with distinct mutagenic consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Chimeric nucleases stimulate gene targeting in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

FokI dimerization is required for DNA cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Structure of the multimodular endonuclease FokI bound to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

12 September 2017

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

14 September 2017

Mammalian gene targeting with designed zinc finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

14 September 2017

Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

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Targeted genome modifications using integrase-deficient lentiviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

21 August 2018

Design, construction and in vitro testing of zinc finger nucleases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

21 August 2018

High-frequency homologous recombination in plants mediated by zinc-finger nucleases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

21 August 2018

Custom zinc-finger nucleases for use in human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834978

21 August 2018

FokI requires two specific DNA sites for cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002164

12 December 2020

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Identifiers

10.1038/MT.2008.233

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

ResearchGate publication ID

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