(Q29308378)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme (English)

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Kevin L Hua

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Philip D Gregory

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Jianbin Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Geoffrey Friedman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Nathaniel S Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Carrie Jiaxin Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jeffrey C Miller

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jenny Jiacheng Yan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Joshua E Babiarz

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Michael C Holmes

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

20 March 2012

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Genome Research

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

22

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

7

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

1316-1326

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

26 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Genome editing with engineered zinc finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted mutagenesis in the silkworm Bombyx mori using zinc finger nuclease mRNA injection

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted mutagenesis in the sea urchin embryo using zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Knockout rats via embryo microinjection of zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

High-frequency modification of plant genes using engineered zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted transgene integration in plant cells using designed zinc finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Progress and prospects: zinc-finger nucleases as gene therapy agents

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Zinc-finger nucleases: the next generation emerges

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

The mechanism of human nonhomologous DNA end joining

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

An improved zinc-finger nuclease architecture for highly specific genome editing

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Mechanism of homologous recombination: mediators and helicases take on regulatory functions

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Historical overview: searching for replication help in all of the rec places

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Initiation of genetic recombination and recombination-dependent replication

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Megabase chromatin domains involved in DNA double-strand breaks in vivo

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

FokI dimerization is required for DNA cleavage

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Homologous pairing and strand exchange in genetic recombination

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Single-strand break repair and genetic disease

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

A rapid and general assay for monitoring endogenous gene modification

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted genome modification in mice using zinc-finger nucleases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Timing is everything: cell cycle control of Rad52

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Zinc finger nuclease technology heralds a new era in mammalian transgenesis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Repair of gaps opposite lesions by homologous recombination in mammalian cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Stimulation of homology-directed gene targeting at an endogenous human locus by a nicking endonuclease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Human gene targeting favors insertions over deletions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Comparison of nonhomologous end joining and homologous recombination in human cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Importance of the cell cycle phase for the choice of the appropriate DSB repair pathway, for genome stability maintenance: the trans-S double-strand break repair model

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

A macaque's-eye view of human insertions and deletions: differences in mechanisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

DNA double-strand break repair: all's well that ends well

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Analysis of DNA double-strand break repair pathways in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Pathways for mitotic homologous recombination in mammalian cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

THE INDUCTION OF MITOTIC RECOMBINATION BY MITOMYCIN C IN USTILAGO AND SACCHAROMYCES

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Single-strand interruptions in replicating chromosomes cause double-strand breaks

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Rescue of arrested replication forks by homologous recombination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Yeast vectors for integration at the HO locus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Single amino acid substitutions uncouple the DNA binding and strand scission activities of Fok I endonuclease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

A general model for genetic recombination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396372

Cell cycle-dependent regulation of double-strand break repair: a role for the CDK

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22434427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GR.122879.111

3 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434427%20AND%20SRC:MED&resulttype=core&format=json