(Q33566358)

28 July 2017

title

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity (English)

1 reference

28 July 2017

6

J Keith Joung

1 reference

28 July 2017

John P Guilinger

1

1 reference

28 July 2017

Vikram Pattanayak

2

1 reference

28 July 2017

Deepak Reyon

3

1 reference

28 July 2017

Shengdar Q Tsai

4

1 reference

28 July 2017

Jeffry D Sander

5

1 reference

28 July 2017

David R Liu

7

1 reference

28 July 2017

publication date

16 February 2014

1 reference

28 July 2017

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28 July 2017

volume

11

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28 July 2017

issue

4

1 reference

28 July 2017

page(s)

429-435

1 reference

https://scigraph.springernature.com/pub.10.1038/nmeth.2845

28 July 2017

exact match

0 references

cites work

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In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites

21 June 2018

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

21 June 2018

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

21 June 2018

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21 June 2018

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A library of TAL effector nucleases spanning the human genome

21 June 2018

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Quantitative analysis of TALE-DNA interactions suggests polarity effects.

21 June 2018

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A TALEN genome-editing system for generating human stem cell-based disease models

21 June 2018

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Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)

21 June 2018

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Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues

21 June 2018

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In vivo genome editing using a high-efficiency TALEN system

21 June 2018

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Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome

21 June 2018

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Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

21 June 2018

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Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs

21 June 2018

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Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs).

21 June 2018

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FLASH assembly of TALENs for high-throughput genome editing

21 June 2018

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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

21 June 2018

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An unbiased genome-wide analysis of zinc-finger nuclease specificity

21 June 2018

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

21 June 2018

1 reference

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Genetic engineering of human pluripotent cells using TALE nucleases

21 June 2018

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Targeted genome editing across species using ZFNs and TALENs

21 June 2018

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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

21 June 2018

1 reference

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Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

A TALE nuclease architecture for efficient genome editing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

How does multiple testing correction work?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

Breaking the code of DNA binding specificity of TAL-type III effectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

A simple cipher governs DNA recognition by TAL effectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins

21 June 2018

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Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

An improved zinc-finger nuclease architecture for highly specific genome editing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010127

Knockout rats generated by embryo microinjection of TALENs.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.2845

TALENs and ZFNs are associated with different mutation signatures

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.2845

Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.2845

TAL effector RVD specificities and efficiencies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24531420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NMETH.2845

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference