(Q46625294)

23 December 2017

title

C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist (English)

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23 December 2017

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4

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23 December 2017

author name string

Lihua Bao

1

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23 December 2017

Iyabo Osawe

2

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23 December 2017

Tipu Puri

3

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23 December 2017

Mark Haas

5

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23 December 2017

Richard J Quigg

6

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23 December 2017

language of work or name

English

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publication date

1 August 2005

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23 December 2017

European Journal of Immunology

published in

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23 December 2017

volume

35

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23 December 2017

issue

8

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23 December 2017

page(s)

2496-2506

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23 December 2017

Complement. First of two parts

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Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr mice

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Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor

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Protection of innate immunity by C5aR antagonist in septic mice

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Cultured human glomerular mesangial cells express the C5a receptor

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The C5a receptor is expressed in normal renal proximal tubular but not in normal pulmonary or hepatic epithelial cells

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7 January 2021

The C5a receptor is expressed by human renal proximal tubular epithelial cells

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7 January 2021

C5a is important in the tubulointerstitial component of experimental immune complex glomerulonephritis

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7 January 2021

Enhanced expression of complement C5a receptor mRNA in human diseased kidney assessed by in situ hybridization

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Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody.

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7 January 2021

Expression of transforming growth factor-beta and tumor necrosis factor-alpha in the plasma and tissues of mice with lupus nephritis

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Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc

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A Proinflammatory Role of IL-18 in the Development of Spontaneous Autoimmune Disease

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C5a initiates the inflammatory cascade in immune complex peritonitis

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Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis

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7 January 2021

Regulatory role of C5a on macrophage migration inhibitory factor release from neutrophils

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7 January 2021

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

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7 January 2021

A new small molecule C5a receptor antagonist inhibits the reverse-passive Arthus reaction and endotoxic shock in rats

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7 January 2021

Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat.

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7 January 2021

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains

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7 January 2021

Excessive Matrix Accumulation in the Kidneys of MRL/lpr Lupus Mice Is Dependent on Complement Activation

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7 January 2021

Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils.

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7 January 2021

High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus

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7 January 2021

Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus.

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7 January 2021

Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity.

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7 January 2021

Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus.

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7 January 2021

Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney.

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7 January 2021

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

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7 January 2021

Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis

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7 January 2021

Negative role of colony-stimulating factor-1 in macrophage, T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice

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7 January 2021

Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation

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https://api.crossref.org/works/10.1002%2FEJI.200526327

7 January 2021

Immune complex glomerulonephritis in C4- and C3-deficient mice

1 reference

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7 January 2021

Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200526327

7 January 2021

Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200526327

7 January 2021

Increased C5a receptor expression in sepsis

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https://api.crossref.org/works/10.1002%2FEJI.200526327

7 January 2021

Identifiers

DOI

10.1002/EJI.200526327

1 reference

23 December 2017

PubMed ID

16052609

1 reference

23 December 2017