(Q46640292)

23 December 2017

title

Proapoptotic and antiapoptotic effects of hyperglycemia: role of insulin signaling (English)

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23 December 2017

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Craig Ricci

1

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23 December 2017

Chian Ju Jong

series ordinal

2

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23 December 2017

Stephen W Schaffer

series ordinal

3

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23 December 2017

publication date

1 April 2008

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23 December 2017

Canadian Journal of Physiology and Pharmacology

published in

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23 December 2017

volume

86

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23 December 2017

issue

4

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23 December 2017

page(s)

166-172

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23 December 2017

Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction

cites work

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Cell death and diabetic cardiomyopathy

21 January 2018

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Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway

21 January 2018

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Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc

21 January 2018

1 reference

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

Diabetic cardiomyocyte dysfunction and myocyte insulin resistance: role of glucose-induced PKC activity

21 January 2018

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Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.

21 January 2018

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High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway

21 January 2018

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The involvement of phosphatidylinositol 3-kinase /Akt signaling in high glucose-induced downregulation of GLUT-1 expression in ARPE cells.

21 January 2018

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Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle.

21 January 2018

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Protection against myocardial ischemia/reperfusion injury by short-term diabetes: enhancement of VEGF formation, capillary density, and activation of cell survival signaling.

21 January 2018

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Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I.

21 January 2018

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PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

21 January 2018

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Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

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Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells

21 January 2018

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High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway.

21 January 2018

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Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner

21 January 2018

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The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

21 January 2018

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Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases

21 January 2018

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Chronically elevated glucose-induced apoptosis is mediated by inactivation of Akt in cultured Müller cells

21 January 2018

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Contradictory effects of short- and long-term hyperglycemias on ischemic injury of myocardium via intracellular signaling pathway

21 January 2018

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Elevated glucose activates protein synthesis in cultured cardiac myocytes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y08-021

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23 December 2017

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23 December 2017