(Q46640868)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Peter Proks

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Frances M Ashcroft

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

publication date

8 August 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

issue

18

1 reference

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5 January 2020

page(s)

2717-2726

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16087682%20AND%20SRC:MED&resulttype=core&format=json

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

5 January 2020

cites work

1 reference

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Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy

21 January 2018

1 reference

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Kir6.2 mutations are a common cause of permanent neonatal diabetes in a large cohort of French patients

21 January 2018

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KCNJ11 activating mutations in Italian patients with permanent neonatal diabetes.

21 January 2018

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High-dose glibenclamide can replace insulin therapy despite transitory diarrhea in early-onset diabetes caused by a novel R201L Kir6.2 mutation

21 January 2018

1 reference

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Relapsing diabetes can result from moderately activating mutations in KCNJ11.

21 January 2018

1 reference

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The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus.

21 January 2018

1 reference

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Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

21 January 2018

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Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

21 January 2018

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Octameric stoichiometry of the KATP channel complex

21 January 2018

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Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

21 January 2018

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A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels

21 January 2018

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A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel

21 January 2018

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Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

21 January 2018

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Electrophysiology of the pancreatic beta-cell

21 January 2018

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Physiological and pathophysiological roles of ATP-sensitive K+ channels

21 January 2018

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Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes

21 January 2018

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Sulphonylurea action revisited: the post-cloning era.

21 January 2018

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Glibenclamide treatment in permanent neonatal diabetes mellitus due to an activating mutation in Kir6.2.

21 January 2018

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Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

21 January 2018

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MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.

21 January 2018

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Adenosine diphosphate as an intracellular regulator of insulin secretion.

21 January 2018

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The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide

21 January 2018

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Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor

21 January 2018

1 reference

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Tandem function of nucleotide binding domains confers competence to sulfonylurea receptor in gating ATP-sensitive K+ channels.

21 January 2018

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Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features

21 January 2018

1 reference

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A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI305

Permanent neonatal diabetes due to paternal germline mosaicism for an activating mutation of the KCNJ11 Gene encoding the Kir6.2 subunit of the beta-cell potassium adenosine triphosphate channel

21 January 2018

1 reference

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Phosphoinositides decrease ATP sensitivity of the cardiac ATP-sensitive K(+) channel. A molecular probe for the mechanism of ATP-sensitive inhibition

21 January 2018

1 reference

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Membrane phospholipid control of nucleotide sensitivity of KATP channels

21 January 2018

1 reference

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ATP modulation of ATP-sensitive potassium channel ATP sensitivity varies with the type of SUR subunit

21 January 2018

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A novel method for measurement of submembrane ATP concentration.

21 January 2018

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Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes.

21 January 2018

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Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets

21 January 2018

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Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

21 January 2018

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Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.

21 January 2018

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Structure and dynamics of the pore of inwardly rectifying K(ATP) channels.

21 January 2018

1 reference

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Sulfonylurea stimulation of insulin secretion

21 January 2018

1 reference

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The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation.

21 January 2018

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Type 2 diabetes mellitus: not quite exciting enough?

21 January 2018

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Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons

21 January 2018

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ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites

21 January 2018

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Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.

21 January 2018

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