(Q46647192)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18409175%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives (English)

1 reference

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5 January 2020

2

1 reference

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5 January 2020

Laura Formentini

4

1 reference

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5 January 2020

Francesco Venturoni

6

1 reference

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5 January 2020

Gökçen Eren

7

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5 January 2020

author name string

Roberto Pellicciari

1

1 reference

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5 January 2020

Gabriele Costantino

3

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5 January 2020

Paola Sabbatini

5

1 reference

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5 January 2020

Daniele Bellocchi

8

1 reference

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5 January 2020

Alberto Chiarugi

9

1 reference

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5 January 2020

Flavio Moroni

10

1 reference

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5 January 2020

publication date

1 June 2008

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5 January 2020

1 reference

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5 January 2020

volume

3

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5 January 2020

issue

6

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5 January 2020

page(s)

914-923

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Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

5 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

3. Life or death decisions: the cast of poly(ADP-ribose)polymerase (PARP) as a therapeutic target for brain ischaemia.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Clinical perspectives of PARP inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Towards new neuroprotective agents: design and synthesis of 4H-thieno[2,3-c] isoquinolin-5-one derivatives as potent PARP-1 inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Two isoindoline alkaloids from the crude drug, the ant lion (the larvae of Myrmeleontidae species).

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Docking studies on PARP-1 inhibitors: insights into the role of a binding pocket water molecule

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800010

7 January 2021

Identifiers

DOI

10.1002/CMDC.200800010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18409175%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference