(Q46648296)

English

Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition

scientific article published on 28 October 2015

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

1 reference

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author name string

Shota Uesugi

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Nozomi Fujisawa

2

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Jun Yoshida

3

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Mitsuru Watanabe

4

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Shingo Dan

5

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Takao Yamori

6

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Yoshihito Shiono

7

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

Ken-ichi Kimura

8

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

publication date

28 October 2015

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

The Journal of Antibiotics

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

69

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

3

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

133-140

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

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Pyrrospirones A and B, apoptosis inducers in HL-60 cells, from an endophytic fungus, Neonectria ramulariae Wollenw KS-246.

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Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation.

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RETRACTED: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

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ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors

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Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

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Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells

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Beyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteins

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Covalent modifiers: an orthogonal approach to drug design

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Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker

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Anthracobic Acids A and B, Two Polyketides, Produced by an Endophytic FungusAnthracobia sp.

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12 December 2020

based on heuristic

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A protective endophyte of maize: Acremonium zeae antibiotics inhibitory to Aspergillus flavus and Fusarium verticillioides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26506860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial activity of pyrrocidines from Acremonium zeae against endophytes and pathogens of maize

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic study of pyrrocidines: first entry to the decahydrofluorene core of pyrrocidines

1 reference

https://pubmed.ncbi.nlm.nih.gov/26506860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/JA.2015.103

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26506860

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