(Q46649179)

23 December 2017

title

The parkinsonism producing neurotoxin MPP+ affects microtubule dynamics by acting as a destabilising factor (English)

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23 December 2017

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parkinsonian syndrome

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2

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23 December 2017

author name string

Graziella Cappelletti

series ordinal

1

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23 December 2017

Rosalba Maci

series ordinal

3

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23 December 2017

language of work or name

English

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publication date

1 August 2005

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23 December 2017

published in

FEBS Letters

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23 December 2017

volume

579

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23 December 2017

page(s)

4781-4786

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23 December 2017

issue

21

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23 December 2017

Molecular pathways to neurodegeneration

cites work

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Role of tau protein in both physiological and pathological conditions.

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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Parkin stabilizes microtubules through strong binding mediated by three independent domains.

21 January 2018

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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21 January 2018

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Influence of MPP+ on the state of tubulin polymerisation in NGF-differentiated PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.07.058

Microtubule assembly is directly affected by MPP(+)in vitro

21 January 2018

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Preparation of modified tubulins

21 January 2018

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Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis

21 January 2018

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Dynamic instability of microtubule growth

21 January 2018

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Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules

21 January 2018

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XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly

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A kinesin-like motor inhibits microtubule dynamic instability

21 January 2018

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Identification of brain proteins that interact with 2-methylnorharman. An analog of the parkinsonian-inducing toxin, MPP+.

21 January 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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Rotenone inhibition of spindle microtubule assembly in mammalian cells.

21 January 2018

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Parkin is recruited to the centrosome in response to inhibition of proteasomes

21 January 2018

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Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head

21 January 2018

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Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

21 January 2018

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Dynamics of axonal microtubules regulate the topology of new membrane insertion into the growing neurites

21 January 2018

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Structural basis for the regulation of tubulin by vinblastine

21 January 2018

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Reconstitution of Physiological Microtubule Dynamics Using Purified Components

21 January 2018

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10.1016/J.FEBSLET.2005.07.058

21 January 2018

Identifiers

DOI

1 reference

23 December 2017

PubMed ID

16098973

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23 December 2017