(Q46667874)

English

The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.

scientific article published in August 2005

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scholarly article

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16120782

The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

amyotrophic lateral sclerosis

0 references

author name string

Burkhard Schütz

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Jens Reimann

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Lucia Dumitrescu-Ozimek

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Karin Kappes-Horn

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Gary E Landreth

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Britta Schürmann

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Andreas Zimmer

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

Michael T Heneka

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 August 2005

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16120782

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

25

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

7805-7812

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

34

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6725264/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of nitric oxide synthase isoforms in spinal cord in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase (iNOS) and nitrotyrosine immunoreactivity in the spinal cords of transgenic mice with a G93A mutant SOD1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanisms of action of PPARs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neurone disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging roles of PPARs in inflammation and immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuro-inflammation as a therapeutic target in amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic Potential of Peroxisome Proliferator-Activated Receptor Agonists for Neurological Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing disease onset and progression in the SOD1 mouse model of ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolidinediones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex genetics of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intraperitoneal injection of Rofecoxib in a mouse model of ALS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histographic analysis of human muscle biopsies with regard to fiber types. 2. Diseases of the upper and lower motor neuron

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of biosynthesis of nitric oxide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16120782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2038-05.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725264&resulttype=core&format=json

12 May 2020

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