(Q46668714)

24 December 2017

title

Is the spliceosome a ribonucleoprotein enzyme? (English)

1 reference

24 December 2017

ribonucleoprotein complex

main subject

spliceosome

0 references

1 reference

John Abelson

1

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24 December 2017

publication date

1 December 2008

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24 December 2017

Nature Structural & Molecular Biology

published in

1 reference

24 December 2017

volume

15

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24 December 2017

page(s)

1235-1237

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24 December 2017

issue

12

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/nsmb1208-1235

exact match

0 references

cites work

Prp8 protein: at the heart of the spliceosome

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Structure and function of an RNase H domain at the heart of the spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Structural elucidation of a PRP8 core domain from the heart of the spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Crystal structure of the -finger domain of Prp8 reveals analogy to ribosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Composition and functional characterization of the yeast spliceosomal penta-snRNP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

U2–U6 RNA folding reveals a group II intron-like domain and a four-helix junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

The question remains: is the spliceosome a ribozyme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

Functional recognition of 5' splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early spliceosome assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1208-1235

31 March 2020

Identifiers

DOI

10.1038/NSMB1208-1235

1 reference

24 December 2017

PubMed ID

19050716

1 reference

24 December 2017