(Q46668855)

English

The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.

scientific article published in April 2009

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scholarly article

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/19117056

The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

1 reference

based on heuristic

inferred from title

cervix uterine cancer

1 reference

based on heuristic

inferred from title

author name string

Pauline J van der Watt

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Christopher P Maske

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Denver T Hendricks

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

M Iqbal Parker

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Lynette Denny

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Dhirendra Govender

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Michael J Birrer

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Virna D Leaner

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

language of work or name

0 references

publication date

1 April 2009

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/19117056

International Journal of Cancer

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

124

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

1829-1840

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear transport as a target for cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of RB and p53 proteins in HPV-positive and HPV-negative cervical carcinoma cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KPNA2 protein expression in invasive breast carcinoma and matched peritumoral ductal carcinoma in situ

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-fidelity mRNA amplification for gene profiling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High prevalence of HPV 16 in South African women with cancer of the cervix and cervical intraepithelial neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear transport and cancer: from mechanism to intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplified RNA synthesized from limited quantities of heterogeneous cDNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear import of HPV11 L1 capsid protein is mediated by karyopherin alpha2beta1 heterodimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classical nuclear localization signals: definition, function, and interaction with importin alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The causal relation between human papillomavirus and cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulating active p53 in the nucleus by inhibition of nuclear export: a novel strategy to promote the p53 tumor suppressor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importin-beta-like nuclear transport receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling to identify markers associated with deregulated hTERT in HPV-transformed keratinocytes and cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of WI-38 cells (WI-38 CT-1) transformed by treatment with Co-60 gamma rays

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleocytoplasmic transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The l2 minor capsid protein of low-risk human papillomavirus type 11 interacts with host nuclear import receptors and viral DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics, 2002

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cluster analysis and display of genome-wide expression patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective induction of apoptosis by leptomycin B in keratinocytes expressing HPV oncogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p53 in cervical carcinoma cells by small molecules.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human papillomavirus quadrivalent (types 6, 11, 16, 18) recombinant vaccine (Gardasil).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics in the year 2000.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear import strategies of high-risk HPV18 L2 minor capsid protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleo-cytoplasmic shuttling of high risk human Papillomavirus E2 proteins induces apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-binding protein 3 expression increases during immortalization of cervical keratinocytes by human papillomavirus type 16 E6 and E7 proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Karyopherins: from nuclear-transport mediators to nuclear-function regulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human genital cancer: synergism between two virus infections or synergism between a virus infection and initiating events?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleo-cytoplasmic transport of proteins as a target for therapeutic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of nuclear transport: central role in development and transformation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/IJC.24146

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6944291&resulttype=core&format=json

13 May 2020

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