(Q46674198)

24 December 2017

title

Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone (English)

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24 December 2017

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Koji Miyanishi

9

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author name string

Yasushi Sato

1

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24 December 2017

Kazuyuki Murase

2

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24 December 2017

Junji Kato

3

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24 December 2017

Masayoshi Kobune

4

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24 December 2017

Tsutomu Sato

5

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24 December 2017

Yutaka Kawano

6

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24 December 2017

Rishu Takimoto

7

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24 December 2017

Kouichi Takada

8

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24 December 2017

Takuya Matsunaga

10

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24 December 2017

Tetsuji Takayama

11

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24 December 2017

Yoshiro Niitsu

12

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24 December 2017

publication date

30 March 2008

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24 December 2017

published in

Nature Biotechnology

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24 December 2017

volume

26

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24 December 2017

issue

4

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24 December 2017

page(s)

431-442

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/nbt1396

exact match

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Beyond the superfamily: the lipocalin receptors

21 January 2018

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Effects of lipopolysaccharides stimulated Kupffer cells on activation of rat hepatic stellate cells

21 January 2018

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

21 January 2018

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7 January 2021

Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum

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7 January 2021

Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking

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7 January 2021

Reversibility of liver fibrosis and cirrhosis following treatment for hepatitis C.

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7 January 2021

Hepatocyte growth factor gene therapy of liver cirrhosis in rats

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7 January 2021

Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats

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7 January 2021

Coexpression of the collagen-binding stress protein HSP47 gene and the alpha 1(I) and alpha 1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis

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7 January 2021

Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis

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7 January 2021

Identification, culture, and characterization of pancreatic stellate cells in rats and humans.

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7 January 2021

Changes in expression of extracellular matrix genes, fibrogenic factors, and actin cytoskeletal organization in retinol treated and untreated vocal fold stellate cells

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7 January 2021

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro

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7 January 2021

Relaxin inhibits effective collagen deposition by cultured hepatic stellate cells and decreases rat liver fibrosis in vivo

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7 January 2021

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

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7 January 2021

Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis

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7 January 2021

Expression profiling reveals off-target gene regulation by RNAi

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7 January 2021

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

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7 January 2021

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

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7 January 2021

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

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7 January 2021

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

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7 January 2021

RNAi-mediated gene silencing in non-human primates.

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7 January 2021

Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer

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7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

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7 January 2021

Transfer of retinol from parenchymal to stellate cells in liver is mediated by retinol-binding protein

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7 January 2021

Transfer of retinol-binding protein from HepG2 human hepatoma cells to cocultured rat stellate cells

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7 January 2021

Hepatic stellate cells uptake of retinol associated with retinol-binding protein or with bovine serum albumin

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7 January 2021

Kinetic parameters of the interactions of retinol with lipid bilayers

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7 January 2021

Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis

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7 January 2021

Pharmacokinetics, tissue distribution, and expression efficiency of plasmid [33P]DNA following intravenous administration of DNA/cationic lipid complexes in mice: use of a novel radionuclide approach

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7 January 2021

Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group

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7 January 2021

Effects on M5076-hepatic metastasis of retinoic acid and N-(4-hydroxyphenyl) retinamide, fenretinide entrapped in SG-liposomes

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7 January 2021

Progress towards in vivo use of siRNAs

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7 January 2021

A morphological study of the early stages of hepatic fibrosis induced by low doses of dimethylnitrosamine in the rat

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7 January 2021

Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis

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7 January 2021

Extracellular matrix binding properties of recombinant fibronectin type II-like modules of human 72-kDa gelatinase/type IV collagenase. High affinity binding to native type I collagen but not native type IV collagen

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7 January 2021

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

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7 January 2021

Development of novel cationic liposomes for efficient gene transfer into peritoneal disseminated tumor

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7 January 2021

A new cationic liposome for efficient gene delivery with serum into cultured human cells: a quantitative analysis using two independent fluorescent probes

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7 January 2021

The synthesis of proteoglycans in fat-storing cells of rat liver

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7 January 2021

Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats

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7 January 2021

Histological grading and staging of chronic hepatitis

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7 January 2021

A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues

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7 January 2021

Identifiers

DOI

10.1038/NBT1396

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24 December 2017

PubMed ID

18376398

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24 December 2017