(Q46682886)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Stereoelectronic properties of spiroquinazolinones in differential PDE7 inhibitory activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Robert J. Doerksen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Robert J Doerksen

series ordinal

2

1 reference

24 December 2017

http://europepmc.org/abstract/MED/18366018

publication date

1 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

Journal of Computational Chemistry

4 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

1945-1954

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

Design of second generation phosphodiesterase 5 inhibitors

4 January 2020

cites work

1 reference

Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development

21 January 2018

1 reference

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

21 January 2018

1 reference

Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

21 January 2018

1 reference

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

21 January 2018

1 reference

A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases

21 January 2018

1 reference

Potential role of phosphodiesterase 7 in human T cell function: comparative effects of two phosphodiesterase inhibitors

21 January 2018

1 reference

Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: advances in the development of specific phosphodiesterase inhibitors

21 January 2018

1 reference

Phosphodiesterase inhibitors in airways disease

21 January 2018

1 reference

Phosphodiesterase 7A: a new therapeutic target for alleviating chronic inflammation?

21 January 2018

1 reference

Phosphodiesterase (PDE) 7 in inflammatory cells from patients with asthma and COPD.

21 January 2018

1 reference

Phosphodiesterases in the CNS: targets for drug development

21 January 2018

1 reference

Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response

21 January 2018

1 reference

Differential distribution of cAMP-specific phosphodiesterase 7A mRNA in rat brain and peripheral organs

21 January 2018

1 reference

Benzyl derivatives of 2,1,3-benzo- and benzothieno[3,2-a]thiadiazine 2,2-dioxides: first phosphodiesterase 7 inhibitors

21 January 2018

1 reference

Synthesis and structure-activity relationships of guanine analogues as phosphodiesterase 7 (PDE7) inhibitors.

21 January 2018

1 reference

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies

21 January 2018

1 reference

Identification of purine inhibitors of phosphodiesterase 7 (PDE7).

21 January 2018

1 reference

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.

21 January 2018

1 reference

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives

21 January 2018

1 reference

Do structurally similar molecules have similar biological activity?

21 January 2018

1 reference

Molecular electrostatic potential of the nucleic acids

21 January 2018

1 reference

22pi smaragdyrin molecular conjugates with aromatic phenylacetylenes and ferrocenes: Syntheses, electrochemical, and photonic properties

21 January 2018

1 reference

Effects of Heterocyclic Aromatic Substituents on Binding Affinities at Two Distinct Sites of Somatostatin Receptors. Correlation with the Electrostatic Potential of the Substituents

21 January 2018

1 reference

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

21 January 2018

1 reference

A fast flexible docking method using an incremental construction algorithm.

21 January 2018

1 reference

Development and validation of a genetic algorithm for flexible docking

21 January 2018

1 reference

Comparative evaluation of eight docking tools for docking and virtual screening accuracy

21 January 2018

1 reference

Evaluation of docking performance: comparative data on docking algorithms

21 January 2018

1 reference

Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7.

21 January 2018

1 reference

Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density

21 January 2018

1 reference

A new mixing of Hartree–Fock and local density‐functional theories

21 January 2018

1 reference

Density-functional thermochemistry. III. The role of exact exchange

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCC.20960

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366018%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference