(Q33341310)

25 July 2017

title

Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7. (English)

1 reference

25 July 2017

5

Hengming Ke

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25 July 2017

Huanchen Wang

1

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25 July 2017

Yudong Liu

series ordinal

2

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25 July 2017

Yuxiang Chen

series ordinal

3

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25 July 2017

Howard Robinson

series ordinal

4

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25 July 2017

language of work or name

English

0 references

publication date

1 July 2005

1 reference

Journal of Biological Chemistry

25 July 2017

published in

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25 July 2017

volume

280

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25 July 2017

issue

35

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25 July 2017

page(s)

30949-30955

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Molecular diversity of cyclic AMP signalling

25 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Phosphodiesterase isozymes: molecular targets for novel antiasthma agents

21 January 2018

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Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

21 January 2018

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Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.

21 January 2018

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Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside

21 January 2018

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The next generation of PDE4 inhibitors

21 January 2018

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Phosphodiesterase 5 inhibitors: current status and potential applications

21 January 2018

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Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: advances in the development of specific phosphodiesterase inhibitors

21 January 2018

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Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease

21 January 2018

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Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Differential distribution of cAMP-specific phosphodiesterase 7A mRNA in rat brain and peripheral organs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M504398200

PDE7A is expressed in human B-lymphocytes and is up-regulated by elevation of intracellular cAMP.

21 January 2018

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Phosphodiesterase 7A-deficient mice have functional T cells.

21 January 2018

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Alternative splicing of the high affinity cAMP-specific phosphodiesterase (PDE7A) mRNA in human skeletal muscle and heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Cloning and characterization of the human and mouse PDE7B, a novel cAMP-specific cyclic nucleotide phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Refolding and purification of recombinant human PDE7A expressed in Escherichia coli as inclusion bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity

21 January 2018

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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The CCP4 suite: programs for protein crystallography

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

21 January 2018

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Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Crystal structure of phosphodiesterase 4D and inhibitor complex(1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

The Crystal Structure of AMP-Bound PDE4 Suggests a Mechanism for Phosphodiesterase Catalysis,

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Structural basis for the activity of drugs that inhibit phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504398200

21 January 2018

Identifiers

DOI

10.1074/JBC.M504398200

1 reference

25 July 2017

1 reference