(Q46691963)

24 December 2017

title

DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation (English)

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24 December 2017

1 reference

Alwin Derijck

1

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24 December 2017

Godfried van der Heijden

2

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24 December 2017

Maud Giele

3

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24 December 2017

Marielle Philippens

4

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24 December 2017

Peter de Boer

5

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24 December 2017

publication date

18 March 2008

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24 December 2017

published in

Human Molecular Genetics

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24 December 2017

volume

17

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24 December 2017

issue

13

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24 December 2017

page(s)

1922-1937

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24 December 2017

Genome maintenance mechanisms for preventing cancer

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Differential usage of non-homologous end-joining and homologous recombination in double strand break repair

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Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response

21 January 2018

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DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

21 January 2018

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Homologous and non-homologous recombination differentially affect DNA damage repair in mice

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Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells

21 January 2018

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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

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A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

21 January 2018

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A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

21 January 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

21 January 2018

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A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 January 2018

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Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

21 January 2018

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Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

21 January 2018

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DNA packaging and organization in mammalian spermatozoa: comparison with somatic cells

21 January 2018

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Genetic lesions induced by chemicals in spermatozoa and spermatids of mice are repaired in the egg

21 January 2018

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Studies on chromosome aberrations in the eggs of mice fertilized in vitro after irradiation. I. Chromosome aberrations induced in sperm after X-irradiation.

21 January 2018

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Dynamics of global gene expression changes during mouse preimplantation development.

21 January 2018

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The molecular foundations of the maternal to zygotic transition in the preimplantation embryo

21 January 2018

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Dynamics of paternal chromatin changes in live one-cell mouse embryo after natural fertilization

21 January 2018

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gammaH2AX signalling during sperm chromatin remodelling in the mouse zygote.

21 January 2018

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Reduced oocyte activation and first cleavage rate after ICSI with spermatozoa from a sterile mouse chromosome mutant.

21 January 2018

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p53-dependent S-phase damage checkpoint and pronuclear cross talk in mouse zygotes with X-irradiated sperm

21 January 2018

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Asymmetry in histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote

21 January 2018

1 reference

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Growing dictyate oocytes, but not early preimplantation embryos, of the mouse display high levels of DNA homologous recombination by single-strand annealing and lack DNA nonhomologous end joining.

21 January 2018

1 reference

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Dramatic changes in the ratio of homologous recombination to nonhomologous DNA-end joining in oocytes and early embryos of Xenopus laevis

21 January 2018

1 reference

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Homologous recombination and DNA-end joining reactions in zygotes and early embryos of zebrafish (Danio rerio) and Drosophila melanogaster

21 January 2018

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The origins, patterns and implications of human spontaneous mutation

21 January 2018

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On the parental origin of de novo mutation in man.

21 January 2018

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Potential adverse effect of sperm DNA damage on embryo quality after ICSI.

21 January 2018

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scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

21 January 2018

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Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Regulation of DNA double-strand break repair pathway choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Heterochromatin and tri-methylated lysine 20 of histone H4 in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Fertilizing ability of DNA-damaged spermatozoa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Topoisomerase II-mediated breaks in spermatozoa cause the specific degradation of paternal DNA in fertilized oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Phosphorylated histone H2AX foci persist on rejoined mitotic chromosomes in normal human diploid cells exposed to ionizing radiation

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Paternally transmitted chromosomal aberrations in mouse zygotes determine their embryonic fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Nuclear dynamics of PCNA in DNA replication and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

RecQ helicases: caretakers of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Cytogenetic study in a mentally retarded child with Bloom syndrome and acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Maternal effects of the scid mutation on radiation-induced transgenerational instability in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Time from insemination to first cleavage predicts developmental competence of human preimplantation embryos in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

A defect in DNA double strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN090

21 January 2018

Identifiers

DOI

10.1093/HMG/DDN090

1 reference

24 December 2017

PubMed ID

18353795

1 reference

24 December 2017