(Q46715173)

English

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

scientific article published in September 2005

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Alzheimer's disease

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John Anthony Hardy

11

object named as

John Hardy

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

7

object named as

Jared Ehrhart

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

13

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Jun Tan

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Europe PubMed Central

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7 January 2020

4

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Takashi Mori

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

12

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Terrence Town

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7 January 2020

Kavon Rezai-Zadeh

1

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Kavon Rezai-Zadeh

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7 January 2020

author name string

Doug Shytle

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Nan Sun

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Huayan Hou

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Deborah Jeanniton

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Kirk Townsend

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Jin Zeng

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

David Morgan

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

John Hardy

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

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publication date

1 September 2005

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

25

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

38

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

8807-8814

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular mechanisms of beta-amyloid production and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer chemoprevention by tea polyphenols.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-alpha expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic β-cell damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single ascending dose study of epigallocatechin gallate in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and function of tumour necrosis factor-alpha-converting enzyme in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tea and Cancer Prevention: Studies in Animals and Humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea catechins as a BACE1 (β-Secretase) inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADAMs family members as amyloid precursor protein alpha-secretases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of green tea-derived catechin on developing versus established atherosclerosis in apolipoprotein E-null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea polyphenols and cancer chemoprevention: multiple mechanisms and endpoints for phase II trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16177050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1521-05.2005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16177050%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

ResearchGate publication ID

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