(Q46718654)

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Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.

scientific article published on 5 March 2008

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

0 references

Taka-aki Koshimizu

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Toshiki Tanaka

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Takeaki Yano

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Akira Hirasawa

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Gozoh Tsujimoto

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

publication date

5 March 2008

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

377

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

4-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

515-522

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

https://scigraph.springernature.com/pub.10.1007/s00210-007-0250-y

0 references

Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of GPR40 in fatty acid action on the beta cell line INS-1E.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic approaches to preserve islet mass in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological effects of Spirometra erinacei plerocercoids in several species of rodents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in partial agonist action at cholecystokinin receptors of mouse and rat are dependent on parameters extrinsic to receptor structure: molecular cloning, expression and functional characterization of the mouse type A cholecystokinin recept

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone is a growth factor for the differentiated pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids induce cholecystokinin secretion through GPR120.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of islet beta-cell proliferation by prolactin in rat islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide I reduces postprandial glycemic excursions in IDDM

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-007-0250-Y

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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