(Q46744627)

English

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

scientific article published on 8 October 2005

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis (English)

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

endoplasmic reticulum

0 references

author name string

A C Riggs

1

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

E Bernal-Mizrachi

2

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

M Ohsugi

3

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

J Wasson

4

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

S Fatrai

5

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

C Welling

6

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

J Murray

7

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

R E Schmidt

8

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

P L Herrera

9

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

M A Permutt

10

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

publication date

8 October 2005

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

48

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

2313-2321

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

11

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

https://scigraph.springernature.com/pub.10.1007/s00125-005-1947-4

0 references

Evidence for linkage on chromosome 4p16.1 in Type 1 diabetes Danish families and complete mutation scanning of the WFS1 (Wolframin) gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous fluorescence monitoring of rapid cycle DNA amplification

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of streptozotocin on the ultrastructure of rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetically programmed selective islet beta-cell loss in diabetic subjects with Wolfram's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association Studies of Genetic Variation in the WFS1 Gene and Type 2 Diabetes in U.K. Populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wolfram (DIDMOAD) syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of hexokinase I but not GLUT1 glucose transporter alters concentration dependence of glucose-stimulated insulin secretion in pancreatic beta-cell line MIN6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wolfram syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herp is dually regulated by both the endoplasmic reticulum stress-specific branch of the unfolded protein response and a branch that is shared with other cellular stress pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of insulin release by glucose is associated with an increase in the number of docked granules in the beta-cells of rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress and the development of diabetes: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16215705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-005-1947-4

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16215705

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46744627&oldid=2129585938"