(Q46746653)

24 December 2017

title

MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model (English)

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24 December 2017

author

Josephine M. Forbes

4

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24 December 2017

Richard Flavell

5

object named as

Richard A Flavell

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24 December 2017

Roger John Davis

6

object named as

Roger J Davis

1 reference

24 December 2017

author name string

Kyoichi Fukuda

1

1 reference

24 December 2017

Greg H Tesch

2

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24 December 2017

Felicia Y Yap

3

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24 December 2017

David J Nikolic-Paterson

7

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24 December 2017

publication date

18 February 2008

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24 December 2017

published in

Laboratory Investigation

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24 December 2017

volume

88

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24 December 2017

issue

4

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24 December 2017

page(s)

398-407

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.2008.10

exact match

0 references

cites work

Prevention of type 1 diabetes: from the view point of beta cell damage

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

A transcriptional inhibitor of TNF-alpha prevents diabetes induced by multiple low-dose streptozotocin injections in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Multiple activation mechanisms of p38alpha mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

The specific p38 mitogen-activated protein kinase pathway inhibitor FR167653 keeps insulitis benign in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Hypertensive end-organ damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Differential regulation of Th1-type and Th2-type cytokine profiles in pancreatic islets of C57BL/6 and BALB/c mice by multiple low doses of streptozotocin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

GLUT2 in pancreatic islets: crucial target molecule in diabetes induced with multiple low doses of streptozotocin in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Induction of tolerance to autoimmune diabetes with islet antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Initial role of macrophage in the development of anti-beta-cell cellular autoimmunity in multiple low-dose streptozotocin-induced diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Is there a role for nitric oxide in beta-cell dysfunction and damage in IDDM?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Inhibition of p38 mitogen-activated protein kinase augments progression of remnant kidney model by activating the ERK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

p38 mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Intracellular Stress Signaling Pathways Activated During Human Islet Preparation and Following Acute Cytokine Exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

Inflammatory mechanisms in diabetes: lessons from the beta-cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Interleukin-1 receptor antagonist prevents low dose streptozotocin induced diabetes in mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Treatment with an interleukin-1 receptor antagonist protein prolongs mouse islet allograft survival

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic β-cells

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

The role of p38alpha mitogen-activated protein kinase activation in renal fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Blockade of p38alpha MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Immunologic Studies on the Induction of Diabetes in Experimental Animals: Cellular Basis for the Induction of Diabetes by Streptozotocin

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

GLUT2 in pancreatic islets: crucial target molecule in diabetes induced with multiple low doses of streptozotocin in mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Beta-cell apoptosis is responsible for the development of IDDM in the multiple low-dose streptozotocin model

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Treatment with anti-T-lymphocyte antibodies prevents induction of insulitis in mice given multiple doses of streptozocin

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Diabetes induced with low doses of streptozotocin is mediated by V beta 8.2+ T-cells

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Functional capacity of macrophages determines the induction of type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Aminoguanidine, an inhibitor of nitric oxide formation, fails to protect against insulitis and hyperglycemia induced by multiple low dose streptozotocin injections in mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

S-methyl-L-thiocitrulline counteracts interleukin 1 beta induced suppression of pancreatic islet function in vitro, but does not protect against multiple low-dose streptozotocin-induced diabetes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

p38 Mitogen-Activated Protein Kinase Inhibition Increases Cytokine Release by Macrophages In Vitro and During Infection In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.10

7 January 2021

10.1038/LABINVEST.2008.10

Identifiers

DOI

1 reference

24 December 2017

PubMed ID

18283273

1 reference

24 December 2017