(Q46775398)

25 December 2017

title

Structure-activity studies on the fluorescent indicator in a displacement assay for the screening of small molecules binding to RNA. (English)

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25 December 2017

author name string

Shiori Umemoto

1

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25 December 2017

Seongwang Im

2

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25 December 2017

Jinhua Zhang

3

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25 December 2017

Masaki Hagihara

4

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25 December 2017

Asako Murata

5

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25 December 2017

Yasue Harada

6

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25 December 2017

Takeo Fukuzumi

7

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25 December 2017

Takahiro Wazaki

8

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25 December 2017

Shin-ichi Sasaoka

9

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25 December 2017

Kazuhiko Nakatani

10

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25 December 2017

language of work or name

English

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publication date

4 July 2012

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25 December 2017

Chemistry—A European Journal

published in

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25 December 2017

volume

18

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25 December 2017

issue

32

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25 December 2017

page(s)

9999-10008

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25 December 2017

Teaching old indicators new tricks.

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Using indicator-displacement assays in test strips and to follow reaction kinetics.

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A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity

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Specific binding of aminoglycoside antibiotics to RNA.

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A high-throughput fluorescence screen to monitor the specific binding of antagonists to RNA targets

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A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine

21 January 2018

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Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders

21 January 2018

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Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay

21 January 2018

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A modified fluorescent intercalator displacement assay for RNA ligand discovery

21 January 2018

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Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors

21 January 2018

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Using pyrene-labeled HIV-1 TAR to measure RNA-small molecule binding

21 January 2018

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Ligand-induced changes in 2-aminopurine fluorescence as a probe for small molecule binding to HIV-1 TAR RNA

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Binding of an aminoacridine derivative to a GAAA RNA tetraloop

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Site-specific fluorescent labeling of RNA molecules by specific transcription using unnatural base pairs

21 January 2018

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A modular strategy for tailoring fluorescent biosensors from ribonucleopeptide complexes

21 January 2018

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Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach.

21 January 2018

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FRET enabled real time detection of RNA-small molecule binding

21 January 2018

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Probing specific RNA bulge conformations by modified fluorescent nucleosides

21 January 2018

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Fluorescent Ribonucleoside as a FRET Acceptor for Tryptophan in Native Proteins

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Fluorescent indicator displacement assay for ligand-RNA interactions

21 January 2018

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RNA as a drug target: chemical, modelling, and evolutionary tools

21 January 2018

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Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges

21 January 2018

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SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets

21 January 2018

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RNA as a Drug Target: The Case of Aminoglycosides

21 January 2018

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21 January 2018

THE HIV-1 REV PROTEIN

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The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

21 January 2018

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The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

21 January 2018

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Alpha helix-RNA major groove recognition in an HIV-1 rev peptide-RRE RNA complex

21 January 2018

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Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.

21 January 2018

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Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

21 January 2018

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Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)

21 January 2018

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Mitoxantrone analogues as ligands for a stem-loop structure of tau pre-mRNA.

21 January 2018

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Molecular aspects on the interaction of protoberberine, benzophenanthridine, and aristolochia group of alkaloids with nucleic acid structures and biological perspectives

21 January 2018

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Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

21 January 2018

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Structure of the HIV-1 nucleocapsid protein bound to the SL3 psi-RNA recognition element

21 January 2018

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Themes in RNA-protein recognition.

21 January 2018

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Photophysics of aminoxanthone derivatives and their application as binding probes for DNA.

21 January 2018

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Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103932

Second generation light-driven molecular motors. Unidirectional rotation controlled by a single stereogenic center with near-perfect photoequilibria and acceleration of the speed of rotation by structural modification

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103932

An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule.

21 January 2018

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A novel two-site binding equation presented in terms of the total ligand concentration.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1002/CHEM.201103932

1 reference

25 December 2017

1 reference

25 December 2017