(Q46779619)

25 December 2017

title

Analysis of PDE6 function using chimeric PDE5/6 catalytic domains (English)

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25 December 2017

author name string

Hakim Muradov

series ordinal

1

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25 December 2017

Kimberly K Boyd

series ordinal

2

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25 December 2017

Nikolai O Artemyev

series ordinal

3

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25 December 2017

publication date

25 October 2005

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25 December 2017

published in

Vision Research

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25 December 2017

volume

46

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25 December 2017

issue

6-7

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25 December 2017

page(s)

860-868

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25 December 2017

The GAF domain: an evolutionary link between diverse phototransducing proteins.

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Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Molecular mechanism of visual transduction

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Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5

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Expression of an active, monomeric catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase (PDE5)

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Cyclic nucleotide phosphodiesterases: relating structure and function

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Identification of the gamma subunit-interacting residues on photoreceptor cGMP phosphodiesterase, PDE6alpha '

7 January 2021

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Partial reconstitution of photoreceptor cGMP phosphodiesterase characteristics in cGMP phosphodiesterase-5.

7 January 2021

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The gamma subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site

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Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase.

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Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivity

7 January 2021

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AIPL1, the protein that is defective in Leber congenital amaurosis, is essential for the biosynthesis of retinal rod cGMP phosphodiesterase

7 January 2021

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Direct interaction of the inhibitory gamma-subunit of Rod cGMP phosphodiesterase (PDE6) with the PDE6 GAFa domains.

7 January 2021

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Structural determinants of the PDE6 GAF A domain for binding the inhibitory gamma-subunit and noncatalytic cGMP

7 January 2021

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Rod photoreceptor cGMP-phosphodiesterase: analysis of alpha and beta subunits expressed in human kidney cells

7 January 2021

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AIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteins

7 January 2021

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Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase

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The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin

7 January 2021

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Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis

7 January 2021

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Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

7 January 2021

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Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

7 January 2021

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A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases

7 January 2021

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10.1016/J.VISRES.2005.09.015

7 January 2021

Identifiers

DOI

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25 December 2017

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25 December 2017