(Q46794494)

25 December 2017

title

Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening (English)

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25 December 2017

author name string

Lei Shi

1

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25 December 2017

Hai-ping Yu

2

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25 December 2017

Yue-yang Zhou

3

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25 December 2017

Jun-qin Du

4

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25 December 2017

Qiang Shen

5

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25 December 2017

Jing-ya Li

6

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25 December 2017

Jia Li

7

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25 December 2017

publication date

1 February 2008

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25 December 2017

Acta Pharmacologica Sinica

published in

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25 December 2017

volume

29

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25 December 2017

page(s)

278-284

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25 December 2017

issue

2

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25 December 2017

https://scigraph.springernature.com/pub.10.1111/j.1745-7254.2008.00737.x

exact match

0 references

cites work

Genome scan for human obesity and linkage to markers in 20q13.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Depot-specific variation in protein-tyrosine phosphatase activities in human omental and subcutaneous adipose tissue: a potential contribution to differential insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Protein tyrosine phosphatase 1B: a new target for the treatment of obesity and associated co-morbidities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Interaction of PTPB with the insulin receptor precursor during its biosynthesis in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

Cellular effects of small molecule PTP1B inhibitors on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2008.00737.X

10.1111/J.1745-7254.2008.00737.X

21 January 2018

Identifiers

DOI

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25 December 2017

Dimensions Publication ID

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25 December 2017