(Q46795047)

English

Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid

scientific article published on 7 November 2005

In more languages

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scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

author name string

Chaekyun Kim

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

Mary C Dinauer

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

publication date

7 November 2005

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

Journal of Leukocyte Biology

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

79

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

223-234

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

Assembly of the phagocyte NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Regulation of neutrophil function by Rac GTPases

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Activation and assembly of the NADPH oxidase: a structural perspective

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

A novel protein kinase target for the lipid second messenger phosphatidic acid

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Protein kinase C: structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic COS-phox cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Protein kinase C zeta phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Activation of the leukocyte NADPH oxidase by protein kinase C in a partially recombinant cell-free system.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Human polymorphonuclear neutrophil activation with arachidonic acid

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Phospholipase C and phosphatidylinositol 3-kinase signaling are involved in the exogenous arachidonic acid-stimulated respiratory burst in human neutrophils

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Protein kinases C translocation responses to low concentrations of arachidonic acid

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Cytosolic phospholipase A2 and its mode of activation in human neutrophils by opsonized zymosan. Correlation between 42/44 kDa mitogen-activated protein kinase, cytosolic phospholipase A2 and NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Activation of the phosphatidylinositol 3-kinase-Akt/protein kinase B signaling pathway in arachidonic acid-stimulated human myeloid and endothelial cells: involvement of the ErbB receptor family

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Chemoattractant receptor-stimulated F-actin polymerization in the human neutrophil is signaled by 2 distinct pathways

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac mediates growth factor-induced arachidonic acid release.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Epidermal growth factor-induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Essential requirement of cytosolic phospholipase A(2) for stimulation of NADPH oxidase-associated diaphorase activity in granulocyte-like cells.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Unique targeting of cytosolic phospholipase A2 to plasma membranes mediated by the NADPH oxidase in phagocytes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Structure of the TPR domain of p67phox in complex with Rac.GTP

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Properties of phagocyte NADPH oxidase p47-phox mutants with unmasked SH3 (Src homology 3) domains: full reconstitution of oxidase activity in a semi-recombinant cell-free system lacking arachidonic acid

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Anionic amphiphile and phospholipid-induced conformational changes in human neutrophil flavocytochrome b observed by fluorescence resonance energy transfer

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox).

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0705371

21 January 2018

Identifiers

10.1189/JLB.0705371

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16275890

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