(Q46801352)

25 December 2017

title

Substrate recognition strategy for botulinum neurotoxin serotype A. (English)

1 reference

25 December 2017

author

Axel T. Brunger

series ordinal

2

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25 December 2017

Mark A Breidenbach

series ordinal

1

object named as

Mark A Breidenbach

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25 December 2017

language of work or name

English

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publication date

12 December 2004

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25 December 2017

published in

Nature

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25 December 2017

volume

432

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25 December 2017

page(s)

925-929

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25 December 2017

issue

7019

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/nature03123

exact match

0 references

cites work

How botulinum and tetanus neurotoxins block neurotransmitter release.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

21 January 2018

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SNARE complex formation is triggered by Ca2+ and drives membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

SNAP receptors implicated in vesicle targeting and fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Crystal structure of botulinum neurotoxin type A and implications for toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Arg(362) and Tyr(365) of the botulinum neurotoxin type a light chain are involved in transition state stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Stability of macromolecular complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Synthesis of substrates and inhibitors of botulinum neurotoxin type A metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Folding intermediates of SNARE complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Substrate-assisted catalysis: molecular basis and biological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Structural Changes Are Associated with SolubleN-Ethylmaleimide-sensitive Fusion Protein Attachment Protein Receptor Complex Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE03123

SNARE motif and neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion.

21 January 2018

1 reference

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7 January 2021

Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Structural determinants of the specificity for synaptic vesicle-associated membrane protein/synaptobrevin of tetanus and botulinum type B and G neurotoxins

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https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Cooperative exosite-dependent cleavage of synaptobrevin by tetanus toxin light chain

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7 January 2021

Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Probing the mechanistic role of glutamate residue in the zinc-binding motif of type A botulinum neurotoxin light chain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Questions about the structure of the botulinum neurotoxin B light chain in complex with a target peptide

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Proteolysis of synthetic peptides by type A botulinum neurotoxin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Structural basis of the action of thermolysin and related zinc peptidases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

A Structural Change Occurs upon Binding of Syntaxin to SNAP-25

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03123

7 January 2021

Identifiers

DOI

10.1038/NATURE03123

1 reference

25 December 2017

Dimensions Publication ID

0 references

1 reference

25 December 2017