(Q46814451)

25 December 2017

title

Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa (English)

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25 December 2017

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Chung CY

1

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25 December 2017

Potikyan G

series ordinal

2

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25 December 2017

Firtel RA

series ordinal

3

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25 December 2017

publication date

1 May 2001

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25 December 2017

published in

Molecular Cell

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25 December 2017

volume

7

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25 December 2017

issue

5

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25 December 2017

page(s)

937-947

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25 December 2017

Role of translocation in the activation and function of protein kinase B

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7 January 2021

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

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7 January 2021

Actin machinery: pushing the envelope.

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7 January 2021

Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization

1 reference

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7 January 2021

PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis

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7 January 2021

In vivo observations of myosin II dynamics support a role in rear retraction

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7 January 2021

Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo

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7 January 2021

Myosin-based cortical tension in Dictyostelium resolved into heavy and light chain-regulated components

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7 January 2021

Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium

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7 January 2021

Chemoattractant-controlled accumulation of coronin at the leading edge of Dictyostelium cells monitored using a green fluorescent protein-coronin fusion protein.

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7 January 2021

Spatial sensing in fibroblasts mediated by 3' phosphoinositides

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7 January 2021

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

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7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

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7 January 2021

The p21Rac/Cdc42-activated kinases (PAKs).

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7 January 2021

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

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7 January 2021

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

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7 January 2021

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

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7 January 2021

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

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7 January 2021

Roles of PAK family kinases.

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7 January 2021

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium

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7 January 2021

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Phosphoinositide signaling and the regulation of membrane trafficking in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

G protein signaling events are activated at the leading edge of chemotactic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

A cell's sense of direction

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

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7 January 2021

Leukocyte polarization in cell migration and immune interactions

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7 January 2021

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

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7 January 2021

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

1 reference

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7 January 2021

A heterotrimeric GTPase-regulated isoform of PI3K and the regulation of its potential effectors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Phosphorylation of the Dictyostelium myosin II heavy chain is necessary for maintaining cellular polarity and suppressing turning during chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

The Akt proto-oncogene links Ras to Pak and cell survival signals

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Spatial control of actin polymerization during neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Direct activation of the fission yeast PAK Shk1 by the novel SH3 domain protein, Skb5.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900247-7

7 January 2021

10.1016/S1097-2765(01)00247-7

Identifiers

DOI

1 reference

25 December 2017

1 reference

25 December 2017