(Q46815329)

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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

Hiroyuki Seimiya

3

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

author name string

Tahara H

1

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

Shin-Ya K

2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

Yamada H

4

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

Tsuruo T

5

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

Ide T

6

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

language of work or name

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publication date

1 March 2006

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

25

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

13

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

1955-1966

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209217

0 references

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

1 reference

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21 January 2018

Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: a circular dichroism study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Interaction of telomestatin with the telomeric single-strand overhang.

1 reference

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21 January 2018

A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity

1 reference

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21 January 2018

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Roles of tumor suppressor and telomere maintenance genes in cancer and aging--an epidemiological study

1 reference

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21 January 2018

Inhibition of telomerase limits the growth of human cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

G-quadruplex DNA: a potential target for anti-cancer drug design

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Crystal structure of parallel quadruplexes from human telomeric DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Control of human telomere length by TRF1 and TRF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

G-tail telomere HPA: simple measurement of human single-stranded telomeric overhangs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

DNA damage foci at dysfunctional telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Monovalent cation-induced structure of telomeric DNA: the G-quartet model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Normal human chromosomes have long G-rich telomeric overhangs at one end

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Inhibition of telomerase by G-quartet DNA structures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

21 January 2018

Immortalization of human uterine leiomyoma and myometrial cell lines after induction of telomerase activity: molecular and phenotypic characteristics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

7 January 2021

based on heuristic

inferred from DOI database lookup

Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

7 January 2021

based on heuristic

inferred from DOI database lookup

G-quadruplex DNA: a target for drug design

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209217

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism-based combination telomerase inhibition therapy

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1209217

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16302000

ResearchGate publication ID

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