(Q46821762)

25 December 2017

title

Kinetic properties of cathepsin D and BACE 1 indicate the need to search for additional beta-secretase candidate(s). (English)

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25 December 2017

author name string

Israel Schechter

series ordinal

1

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25 December 2017

Etty Ziv

series ordinal

2

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25 December 2017

publication date

1 March 2008

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25 December 2017

published in

Biological Chemistry

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25 December 2017

volume

389

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25 December 2017

issue

3

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25 December 2017

page(s)

313-320

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25 December 2017

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Cathepsin D displays in vitro beta-secretase-like specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Processing of the Pre‐β‐amyloid Protein by Cathepsin d is Enhanced by a Familial Alzheimer's Disease Mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

The two sides of enzyme-substrate specificity: lessons from the aspartic proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Biosynthesis of lysosomal endopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Inhibition of beta-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease

21 January 2018

1 reference

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Tumor suppressor gene mutations in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

An inhibitor binding pocket distinct from the catalytic active site on human beta-APP cleaving enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

The endosomal-lysosomal system of neurons: new roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Isolation and characterization of bovine brain cathepsin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.025

21 January 2018

Identifiers

DOI

10.1515/BC.2008.025

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25 December 2017

PubMed ID

18177262

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25 December 2017