(Q46829877)

25 December 2017

title

The mechanism of inhibition of topoisomerase IV by quinolone antibacterials (English)

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25 December 2017

main subject

quinolones

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author

Nicholas R. Cozzarelli

series ordinal

2

object named as

Cozzarelli NR

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25 December 2017

author name string

Khodursky AB

series ordinal

1

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25 December 2017

language of work or name

English

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publication date

1 October 1998

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25 December 2017

Journal of Biological Chemistry

published in

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25 December 2017

volume

273

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25 December 2017

issue

42

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25 December 2017

page(s)

27668-27677

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25 December 2017

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

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1 reference

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A Sign Inversion Mechanism for Enzymatic Supercoiling of DNA

21 January 2018

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Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones

21 January 2018

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Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates

21 January 2018

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Topoisomerase IV is a target of quinolones in Escherichia coli

21 January 2018

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Bacterial diversity based on type II DNA topoisomerase genes

21 January 2018

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The role of topoisomerase IV in partitioning bacterial replicons and the structure of catenated intermediates in DNA replication

21 January 2018

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Roles of topoisomerase IV and DNA gyrase in DNA unlinking during replication in Escherichia coli

21 January 2018

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Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

21 January 2018

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Sites of reaction of Escherichia coli DNA gyrase on pBR322 in vivo as revealed by oxolinic acid-induced plasmid linearization

21 January 2018

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DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex.

21 January 2018

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Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase

21 January 2018

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DNA gyrase and topoisomerase IV on the bacterial chromosome: quinolone-induced DNA cleavage.

21 January 2018

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Cloning of the DNA gyrase genes under tac promoter control: overproduction of the gyrase A and B proteins

21 January 2018

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DNA synthesis inhibition and the induction of protein X in Escherichia coli

21 January 2018

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Antitopoisomerase drug action and resistance

21 January 2018

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Repair of DNA double-strand breaks in Escherichia coli, which requires recA function and the presence of a duplicate genome

21 January 2018

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Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

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Topoisomerase IV, not gyrase, decatenates products of site-specific recombination in Escherichia coli

21 January 2018

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Repair of DNA double-strand breaks in Escherichia coli cells requires synthesis of proteins that can be induced by UV light

21 January 2018

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Degradation of individual chromosomes in recA mutants of Escherichia coli

21 January 2018

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SeqA: a negative modulator of replication initiation in E. coli

21 January 2018

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Isolation and characterisation of a strain carrying a conditional lethal mutation in the cou gene of Escherichia coli K12

21 January 2018

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Contrasting enzymatic activities of topoisomerase IV and DNA gyrase from Escherichia coli

21 January 2018

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Molecular cloning and characterization of acrA and acrE genes of Escherichia coli

21 January 2018

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New topoisomerase essential for chromosome segregation in E. coli.

21 January 2018

1 reference

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gyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase.

21 January 2018

1 reference

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21 January 2018

Bacteria on the rampage

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.42.27668

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25 December 2017

1 reference

25 December 2017