(Q46846341)

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Anti-P-glycoprotein antibody-induced apoptosis of activated peripheral blood lymphocytes: a possible role of P-glycoprotein in lymphocyte survival

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

Anti-P-glycoprotein antibody-induced apoptosis of activated peripheral blood lymphocytes: a possible role of P-glycoprotein in lymphocyte survival (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

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1 reference

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author name string

S Gollapud

1

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

S Gupta

2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

publication date

1 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

Journal of Clinical Immunology

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

21

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

6

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

420-430

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

https://scigraph.springernature.com/pub.10.1023/a:1013177710941

0 references

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular ATP, a switch in the decision between apoptosis and necrosis.

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multidrug resistance (mdr1) gene product functions as an ATP channel

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of TNF-alpha-induced ceramide generation and apoptosis in resistant human leukemia KG1a cells by the P-glycoprotein blocker PSC833.

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide transport by the multidrug resistance pump

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

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Monoclonal antibodies against P-glycoprotein, an MDR1 gene product, inhibit interleukin-2 release from PHA-activated lymphocytes

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

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Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

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Activation interferes with the APO-1 pathway in mature human T cells.

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein expression and function in circulating blood cells from normal volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistant gene 1 product in human T cell subsets: role of protein kinase C isoforms and regulation by cyclosporin A

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by IL-2 withdrawal is associated with an intracellular acidification

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: a role in cytotoxic effector function

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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Caspases: enemies within

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https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein (MDR 1 gene product) in cells of the immune system: its possible physiologic role and alteration in aging and human immunodeficiency virus-1 (HIV-1) infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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Chromatin condensation during apoptosis requires ATP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-dependent steps in apoptotic signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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The IL-2/IL-2 receptor system: a current overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

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Isolation and expression of a complementary DNA that confers multidrug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An apoptotic endonuclease activated either by decreasing pH or by increasing calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased function of P-glycoprotein in T lymphocyte subsets of aging mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug-resistance phenotype of a subpopulation of T-lymphocytes without drug selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of ion transport perturbations caused by hu MDR 1 protein overexpression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: intracellular signaling by proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New mechanisms of hormone secretion: MDR-like gene products as extrusion pumps for hormones?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a multidrug-resistance gene in human tumors and tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas and Fas ligand: a death factor and its receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2: prevention of apoptosis as a mechanism of drug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selection for drug resistance results in resistance to Fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of ceramide in coordinating cellular responses to stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death receptors: signaling and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11811787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1013177710941

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/11811787

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