(Q46849623)

25 December 2017

title

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs (English)

1 reference

25 December 2017

author

Marco Radi

1

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25 December 2017

José A. Esté

11

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25 December 2017

Mercedes Armand-Ugón

13

Mercedes Armand-Ugón

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Imma Clotet-Codina

12

Imma Clotet-Codina

1 reference

25 December 2017

Montserrat Terrazas

Montserrat Terrazas

8

0 references

Chiara Falciani

Chiara Falciani

2

0 references

Giovanni Maga

Giovanni Maga

5

1 reference

ORCID Public Data File 2021

Maurizio Botta

14

Maurizio Botta

1 reference

25 December 2017

author name string

Lorenzo Contemori

3

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25 December 2017

Elena Petricci

4

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25 December 2017

Alberta Samuele

6

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25 December 2017

Samantha Zanoli

7

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25 December 2017

Marinunzia Castria

9

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25 December 2017

Andrea Togninelli

10

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25 December 2017

publication date

1 April 2008

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25 December 2017

published in

ChemMedChem

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25 December 2017

volume

3

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25 December 2017

issue

4

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25 December 2017

page(s)

573-593

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25 December 2017

Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular risk

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Highly active antiretroviral therapy: current state of the art, new agents and their pharmacological interactions useful for improving therapeutic outcome

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7 January 2021

Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: a new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.

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7 January 2021

The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance

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7 January 2021

Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Synthesis and biological evaluation of 2-methoxy- and 2-methylthio-6-[2'-alkylamino)ethyl]-4(3H)-pyrimidinones with anti-rubella virus activity.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

A Versatile Route to C-6 Arylmethyl-FunctionalizedS-DABO and Related Analogues

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https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Parallel solution-phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines

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https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Synthesis and biological evaluation of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines as new rubella virus inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Discovery of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase Competing with the Nucleotide Substrate

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

HIV-1 reverse transcriptase resistance to nonnucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Docking of non-nucleoside inhibitors: neotripterifordin and its derivatives to HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 V

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700198

7 January 2021

Identifiers

DOI

10.1002/CMDC.200700198

1 reference

25 December 2017

1 reference

25 December 2017